885224-71-5Relevant academic research and scientific papers
Synthesis of functionalized cyclopentenes through catalytic asymmetric [3+2] cycloadditions of allenes with enones
Wilson, Jonathan E.,Fu, Gregory C.
, p. 1426 - 1429 (2006)
(Chemical Equation Presented) A phosphepine catalyst mediates enantioselective [3+2] cycloadditions of allenes with a variety of β-substituted α,β-unsaturated enones to produce highly functionalized cyclopentenes that contain two contiguous stereocenters (see scheme). Surprisingly, opposite regioisomers are produced as compared to reactions with β-unsubstituted enones.
