885272-77-5

Basic information

• Product Name: 2-(4-BROMO-PHENYL)-4,5,6,7-TETRAHYDRO-OXAZOLO[4,5-C]PYRIDINE
• Synonyms: 2-(4-BROMO-PHENYL)-4,5,6,7-TETRAHYDRO-OXAZOLO[4,5-C]PYRIDINE
• CAS NO: 885272-77-5
• Molecular Formula: C₁₂H₁₁BrN₂O
• Molecular Weight: 279.13
• Mol File: 885272-77-5.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 410.2±55.0 °C(Predicted)
• Appearance: /
• Density: 1.470±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• PKA: 6.98±0.20(Predicted)
• CAS DataBase Reference: 2-(4-BROMO-PHENYL)-4,5,6,7-TETRAHYDRO-OXAZOLO[4,5-C]PYRIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-BROMO-PHENYL)-4,5,6,7-TETRAHYDRO-OXAZOLO[4,5-C]PYRIDINE(885272-77-5)
• EPA Substance Registry System: 2-(4-BROMO-PHENYL)-4,5,6,7-TETRAHYDRO-OXAZOLO[4,5-C]PYRIDINE(885272-77-5)

Safety Data

• Hazardous Substances Data: 885272-77-5(Hazardous Substances Data)

Usage

General Description

2-(4-Bromo-phenyl)-4,5,6,7-tetrahydro-oxazolo[4,5-c]pyridine is a chemical compound with a molecular formula C14H14BrNO. It is a heterocyclic compound with a bicyclic structure containing a pyridine and oxazole ring. 2-(4-BROMO-PHENYL)-4,5,6,7-TETRAHYDRO-OXAZOLO[4,5-C]PYRIDINE is commonly used in pharmaceutical research and drug development due to its potential biological activity. It may have applications in the treatment of various medical conditions, although further research is needed to fully understand its properties and potential uses.

Upstream product

• 586-75-4 4-chlorobenzoyl chloride 
• 6320-39-4 3-aminopyridin-4-ol 
• 1017781-96-2 2-(4-bromo-phenyl)-5-methyl-4,5,6,7-tetrahydro-oxazolo[4,5-c]pyridine 
• 1354910-38-5 C₁₃H₁₀BrN₂O⁽¹⁺⁾*I^(1-) 
• 934331-03-0 C₁₂H₉BrN₂O₂ 
• 934331-04-1 2-(4-bromophenyl)[1,3]oxazolo[4,5-c]pyridine 

Downstream Products

• 1354910-14-7 4-[2-(4-bromo-phenyl)-6,7-dihydro-4H-oxazolo[4,5-c]pyridine-5-yl]-butyric acid t-butyl ester 
• 1354910-36-3 2-(4-bromo-phenyl)-6,7-dihydro-4H-oxazolo[4,5-c]pyridine-5-carboxylic acid t-butyl ester 
• 1354910-12-5 3-[2-(4-bromo-phenyl)-6,7-dihydro-4H-oxazolo[4,5-c]pyridine-5-yl]-propionic acid t-butyl ester 
• 1354910-27-2 C₂₅H₂₄F₂N₂O₃ 
• 1354910-28-3 C₂₅H₂₆F₂N₂O₃ 
• 1354910-13-6 3-{2-[4-(benzyloxy)-phenyl]-6,7-dihydro-4H-oxazolo[4,5-c]pyridine-5-yl}-propionic acid t-butyl ester 
• 1354905-92-2 3-{2-[4-(benzyloxy)-phenyl]-6,7-dihydro-4H-oxazolo[4,5-c]pyridine-5-yl}-propionic acid 
• 1354910-15-8 4-{2-[4-(2,3-difluoro-benzyloxy)-phenyl]-6,7-dihydro-4H-oxazolo[4,5-c]pyridine-5-yl}-butyric acid t-butyl ester 
• 1354906-02-7 4-{2-[4-(2,3-difluoro-benzyloxy)-phenyl]-6,7-dihydro-4H-oxazolo[4,5-c]pyridine-5-yl}-butyric acid 
• 1354910-18-1 tert-butyl 2-(4-hydroxyphenyl)-6,7-dihydrooxazolo[4,5-c]pyridine-5(4H)-carboxylate 
• 1354910-19-2 2-[4-(4-trifluoromethyl-benzyloxy)-phenyl]-6,7-dihydro-4H-oxazolo[4,5-c]pyridine-5-carboxylic acid t-butyl ester 
• 1354910-40-9 2-[4-(4-trifluoromethyl-benzyloxy)-phenyl]-6,7-dihydro-4H-oxazolo[4,5-c]pyridine 

Relevant articles and documents

FUSED HETEROCYCLIC DERIVATIVES AS S1P MODULATORS

The present invention relates to a fused heterocyclic derivative of the formula (I) The variables R1-R4, z, A, Q, X and Y are as defined in the claims. The following heterocycles are exemplified substructures of formula (I): The compounds of formula (I) are modulators of the S1P receptor (Sphingosine-1-phosphate receptor), More specifically, they are agonists of S1P5. The compounds have therapeutic use in treatment of cognitive disorders, age-relate cognitive decline and dementia.