885280-00-2 Usage
Uses
Used in Pharmaceutical Research:
6-BROMO-1H-BENZOIMIDAZOLE-2-CARBOXYLIC ACID METHYL ESTER is used as a key intermediate in the synthesis of various pharmaceutical compounds due to its unique chemical structure and properties.
Used in Organic Synthesis:
In the field of organic synthesis, 6-BROMO-1H-BENZOIMIDAZOLE-2-CARBOXYLIC ACID METHYL ESTER serves as a versatile building block for the creation of complex organic molecules, contributing to the advancement of chemical research and development.
Used in Medicinal Development:
6-BROMO-1H-BENZOIMIDAZOLE-2-CARBOXYLIC ACID METHYL ESTER is used as a potential candidate for the development of new medications, leveraging its anti-inflammatory and antifungal properties to address various health conditions.
Used in Biochemical Research:
6-BROMO-1H-BENZOIMIDAZOLE-2-CARBOXYLIC ACID METHYL ESTER is utilized as a valuable tool in biochemical research, exhibiting inhibitory activity against certain enzymes, which aids in understanding enzyme functions and developing enzyme-targeted therapies.
Used in Enzyme Inhibition Studies:
In enzyme inhibition studies, 6-BROMO-1H-BENZOIMIDAZOLE-2-CARBOXYLIC ACID METHYL ESTER is employed as an inhibitor to study the effects of enzyme inhibition on biological processes and the development of enzyme-targeted drugs.
Check Digit Verification of cas no
The CAS Registry Mumber 885280-00-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,8,5,2,8 and 0 respectively; the second part has 2 digits, 0 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 885280-00:
(8*8)+(7*8)+(6*5)+(5*2)+(4*8)+(3*0)+(2*0)+(1*0)=192
192 % 10 = 2
So 885280-00-2 is a valid CAS Registry Number.
InChI:InChI=1/C9H7BrN2O2/c1-14-9(13)8-11-6-3-2-5(10)4-7(6)12-8/h2-4H,1H3,(H,11,12)
885280-00-2Relevant articles and documents
2-Arylindoles as gonadotropin releasing hormone (GnRH) antagonists: Optimization of the tryptamine side chain
Young, Jonathan R.,Huang, Song X.,Walsh, Thomas F.,Wyvratt Jr., Matthew J.,Yang, Yi Tien,Yudkovitz, Joel B.,Cui, Jisong,Mount, George R.,Ren, Rena Ning,Wu, Tsuei-Ju,Shen, Xiaolan,Lyons, Kathryn A.,Mao, An-Hua,Carlin, Josephine R.,Karanam, Bindhu V.,Vincent, Stella H.,Cheng, Kang,Goulet, Mark T.
, p. 827 - 832 (2002)
A series of 2-arylindoles containing novel heteroaromatic substituents on the tryptamine tether, based on compound 1, was prepared and evaluated for their ability to act as gonadotropin releasing hormone (GnRH) antagonists. Successful modifications of 1 included chain length variation (reduction) and replacement of the pyridine with heteroaromatic groups. These alterations culminated in the discovery of compound 27kk which had excellent in vitro potency and oral efficacy in rodents.