885324-90-3Relevant academic research and scientific papers
5-Arylethynyl-2′-deoxyuridines, compounds active against HSV-1
Skorobogatyi, Mikhail V.,Ustinov, Alexei V.,Stepanova, Irina A.,Pchelintseva, Anna A.,Petrunina, Anna L.,Andronova, Valeriya L.,Galegov, Georgi A.,Malakhov, Andrei D.,Korshun, Vladimir A.
, p. 1091 - 1096 (2008/02/02)
Three new 5-arylethynyl-2′-deoxyuridines containing bulky aryls have been prepared and tested against HSV-1 in Vero cells. The introduction of a substituent in the phenyl group of an inactive compound, 5-phenylethynyl- 2′-deoxyuridine, leads to the appear
Synthesis and evaluation of anti-HSV activity of new 5-alkynyl-2′- deoxyuridines
Pchelintseva,Skorobogatyj,Petrunina,Andronova,Galegov,Astakhova,Ustinov,Malakhov,Korshun, Vladimir A.
, p. 923 - 926 (2007/10/03)
Eight 5-alkynyl-2′deoxyuridines containing different bulky substituents have been prepared and tested against HSV-1 in Vero cells. The compounds show positive antiviral activity. There is no obvious correlation between activity and substituent size. The n
