88533-86-2Relevant academic research and scientific papers
The stereoselective Horner-Wittig reaction with phoshine oxides: Synthesis of hindered Z alkenes via Luche reduction
Hutton,Jolliff,Mitchell,Warren
, p. 7905 - 7908 (2007/10/02)
The natural anti selectivity of the Horner-Wittig reaction with phospine oxides is reduced when there is a branched chain next to the new C=C double bond. A better approach is Luche reduction of the corresponding ketones which gives high anti selectivity when the branched chain is placed on the side chain next to the phosphine oxide.
CIS-OLEFINS FROM THE HORNER-WITTIG REACTION; ORIGIN AND OPTIMISATION OF STEREOCHEMISTRY
Buss, Antony D.,Warren, Stuart
, p. 3931 - 3934 (2007/10/02)
Conditions are described to produce high yields of erythro Horner-Wittig intermediates: stereospecific elimination gives cis-alkenes.
