88546-74-1

Basic information

• Product Name: H-D-PRO-PHE-ARG-CHLOROMETHYLKETONE
• Synonyms: H-D-PRO-PHE-ARG-CHLOROMETHYLKETONE;DPRO-PHE-ARG-CHLOROMETHYLKETONE;DPRO-PHE-ARG-CMK
• CAS NO: 88546-74-1
• Molecular Formula: C21H31ClN6O3
• Molecular Weight: 450.96
• Mol File: 88546-74-1.mol
• Article Data: 0

Chemical Properties

• Appearance: /
• Storage Temp.: -15°C
• CAS DataBase Reference: H-D-PRO-PHE-ARG-CHLOROMETHYLKETONE(CAS DataBase Reference)
• NIST Chemistry Reference: H-D-PRO-PHE-ARG-CHLOROMETHYLKETONE(88546-74-1)
• EPA Substance Registry System: H-D-PRO-PHE-ARG-CHLOROMETHYLKETONE(88546-74-1)

Safety Data

• Hazardous Substances Data: 88546-74-1(Hazardous Substances Data)

Usage

General Description

H-D-PRO-PHE-ARG-CHLOROMETHYLKETONE is a chemical compound that acts as a specific irreversible inhibitor of caspase-3, a key enzyme involved in the process of apoptosis, or programmed cell death. It contains the amino acids proline, phenylalanine, and arginine, along with a chloromethylketone group that specifically binds to the active site of caspase-3, preventing its normal function and ultimately leading to cell death. H-D-PRO-PHE-ARG-CHLOROMETHYLKETONE has been used in research studies to investigate the role of caspase-3 in various biological processes and diseases, including cancer and neurodegenerative disorders. Due to its potent inhibitory effects on caspase-3, H-D-PRO-PHE-ARG-CHLOROMETHYLKETONE may have potential applications in the development of new therapeutic strategies for these conditions.