885653-45-2

Upstream product

• 91419-52-2 1-tert-butoxycarbonyl-4-cyanopiperidine 
• 104-83-6 1-Chloro-4-(chloromethyl)benzene 
• 885500-39-0 4-(4-chlorobenzyl)-4-cyanopiperidine-1-carboxylic acid tert-butyl ester 

Downstream Products

• 885653-44-1 C-[4-(4-chlorobenzyl)piperidin-4-yl]methylamine 
• 1229828-25-4 6-Chloro-2-[4-(4-chloro-benzyl)-4-cyano-piperidine-1-carbonyl]-2,3-dihydro-benzo[1,4]oxazine-4-carboxylic acid tert-butyl ester 

Relevant academic research and scientific papers

COMPOUNDS, COMPOSITIONS, AND METHODS OF USE

Described herein are compounds that act as CYP46A1 inhibitors, compositions comprising these compounds, and methods of their use into treating neurodegenerative diseases and the like, or a pharmaceutically active salt thereof. The present invention relates to compounds represented by the formula wherein each symbol is as defined in the specification, or a pharmaceutically active salt thereof.

NOVEL BENZODIOXANE AND BENZOXAZINE DERIVATIVES USEFUL AS CC CHEMOKINE RECEPTOR LIGANDS

The present invention relates to benzodioxane and benzoxazine derivatives that act as ligands for CC chemokine receptors, such as CCR1. The invention also relates to methods of preparing the compounds, compositions containing the compounds, and to methods of treatment using the compounds.