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885672-85-5

[1,1'-Biphenyl]-4-carboxamide, N-[(1S)-1-(4-chlorophenyl)-3-(dimethylamino)propyl]- is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 885672-85-5 Structure

  • Basic information

    1. Product Name: [1,1'-Biphenyl]-4-carboxamide, N-[(1S)-1-(4-chlorophenyl)-3-(dimethylamino)propyl]-
    2. Synonyms:
    3. CAS NO:885672-85-5
    4. Molecular Formula: C24H25ClN2O
    5. Molecular Weight: 392.928
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 885672-85-5.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: [1,1'-Biphenyl]-4-carboxamide, N-[(1S)-1-(4-chlorophenyl)-3-(dimethylamino)propyl]-(CAS DataBase Reference)
    10. NIST Chemistry Reference: [1,1'-Biphenyl]-4-carboxamide, N-[(1S)-1-(4-chlorophenyl)-3-(dimethylamino)propyl]-(885672-85-5)
    11. EPA Substance Registry System: [1,1'-Biphenyl]-4-carboxamide, N-[(1S)-1-(4-chlorophenyl)-3-(dimethylamino)propyl]-(885672-85-5)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 885672-85-5(Hazardous Substances Data)

885672-85-5 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 885672-85-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,8,5,6,7 and 2 respectively; the second part has 2 digits, 8 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 885672-85:
(8*8)+(7*8)+(6*5)+(5*6)+(4*7)+(3*2)+(2*8)+(1*5)=235
235 % 10 = 5
So 885672-85-5 is a valid CAS Registry Number.

885672-85-5Downstream Products

885672-85-5Relevant articles and documents

Novel and potent small-molecule urotensin II receptor agonists

Lehmann, Fredrik,Currier, Erika A.,Clemons, Bryan,Hansen, Lars K.,Olsson, Roger,Hacksell, Uli,Luthman, Kristina

experimental part, p. 4657 - 4665 (2009/12/06)

A series of analogs of the non-peptidic urotensin II receptor agonist N-[1-(4-chlorophenyl)-3-(dimethylamino)propyl]-4-phenylbenzamide (FL104) has been synthesized and evaluated pharmacologically. The enantiomers of the two most potent racemic analogues were obtained from the corresponding diastereomeric mandelic amides. In agreement with previously observed SAR, most of the agonist potency resided in the (S) enantiomers. The most potent UII receptor agonist in the new series was (S)-N-[3-dimethylamino-1-(2-naphthyl)propyl]-4-(4-chlorophenyl)benzamide (EC50 = 23 nM at the urotensin II receptor).

UII-MODULATING COMPOUNDS AND THEIR USE

-

Page/Page column 75-76, (2008/12/05)

Disclosed herein are novel aromatic-containing compounds and methods for using various aromatic-containing compounds for treatment and prevention of diseases and disorders related to the Urotensin II receptor.

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