885696-49-1Relevant academic research and scientific papers
Asymmetric Mannich reaction of malonates with imines catalyzed by a chiral calcium complex
Poisson, Thomas,Tsubogo, Tetsu,Yamashita, Yasuhiro,Kobayashi, Shu
scheme or table, p. 963 - 965 (2010/05/19)
(Chemical Equation Presented) Achiral calcium complex was found to be effective for the Mannich reactions of malonates with N-Boc imines. The desired adducts were obtained in excellent yields (up to 95%) with moderate to good enantioselectivities (up to 77% ee).
