885703-32-2

Upstream product

• 15896-04-5 1,2-divinylethylene carbonate 
• 885703-28-6 (S,S)-5-(1-(4-methoxy-2,3-dimethylphenoxy)allyl)furan-2(5H)-one 
• 885703-30-0 (S)-5-((1S,7R,E)-1,7-dihydroxyoct-2-enyl)furan-2(5H)-one 
• 885703-25-3 (S,S)-4-(4-methoxy-2,3-dimethylphenoxy)hexa-1,5-dien-3-ol 
• 885703-29-7 (S)-5-((S)-1-hydroxyallyl)furan-2(5H)-one 
• 885703-31-1 (5R)-5-((1S,7R,E)-1,7-dihydroxyoct-2-enyl)-4-(phenylthio)-dihydrofuran-2(3H)-one 
• 885703-27-5 (S,S)-4-(4-methoxy-2,3-dimethylphenoxy)hexa-1,5-dien-3-yl acrylate 

Relevant academic research and scientific papers

Palladium-catalyzed asymmetric allylic alkylation of meso- and dl-1,2-divinylethylene carbonate

The palladium-catalyzed asymmetric allylic alkylation of a 1:1 mixture of DL- and meso-1,2-divinylethylene carbonate is reported. For the first time, both the ionization and nucleophilic addition steps of the catalytic cycle act as enantiodiscriminating steps to give a single product in high enantiomeric excess. The reactions proceed in >98% ee to efficiently generate useful chiral building blocks from acrolein. The absolute and relative configurations of iso-cladospolide B and 11-epi-iso-cladospolide B were verified by total synthesis, solving an apparent discrepancy in the literature. Copyright