885953-12-8

Basic information

• Product Name: 8-BROMO-1,3,4,5-TETRAHYDROBENZO[B]AZEPINE-2-ONE
• Synonyms: 8-BROMO-1,3,4,5-TETRAHYDROBENZO[B]AZEPINE-2-ONE;2H-1-BENZAZEPIN-2-ONE, 8-BROMO-1,3,4,5-TETRAHYDRO-;8-bromo-4,5-dihydro-1H-benzo[b]azepin-2(3H)-one
• CAS NO: 885953-12-8
• Molecular Formula: C10H10BrNO
• Molecular Weight: 240.1
• Product Categories: pharmacetical
• Mol File: 885953-12-8.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 370.2°C at 760 mmHg
• Flash Point: 177.7°C
• Appearance: /
• Density: 1.475g/cm³
• Vapor Pressure: 1.13E-05mmHg at 25°C
• Refractive Index: 1.58
• CAS DataBase Reference: 8-BROMO-1,3,4,5-TETRAHYDROBENZO[B]AZEPINE-2-ONE(CAS DataBase Reference)
• NIST Chemistry Reference: 8-BROMO-1,3,4,5-TETRAHYDROBENZO[B]AZEPINE-2-ONE(885953-12-8)
• EPA Substance Registry System: 8-BROMO-1,3,4,5-TETRAHYDROBENZO[B]AZEPINE-2-ONE(885953-12-8)

Safety Data

• Hazardous Substances Data: 885953-12-8(Hazardous Substances Data)

Usage

InChI:InChI=1/C10H10BrNO/c11-8-5-4-7-2-1-3-10(13)12-9(7)6-8/h4-6H,1-3H2,(H,12,13)

Upstream product

• 32281-97-3 7-bromo-3,4-dihydro-2H-naphthalen-1-one 
• 877263-91-7 7-bromo-N-hydroxy-3,4-dihydronaphthalen-1(2H)-imine 

Downstream Products

• 205584-61-8 8-bromo-2,3,4,5-tetrahydro-1H-benzo[b]azepine 
• 142852-50-4 Zanapezil 
• 167090-30-4 8-phenyl-1,3,4,5-tetrahydro-benzo[b]azepin-2-one 

Relevant articles and documents

SUBSTITUTED 1,1'-BIPHENYL COMPOUNDS AND METHODS USING SAME

The present invention includes substituted 1,1'-biphenyl compounds, analogues thereof, and compositions comprising the same. In one aspect, the compounds contemplated in the invention can be used to treat, ameliorate, or prevent hepatitis B virus (HBV) and/or hepatitis D virus (HDV) infections in a patient. In another aspect, the compounds contemplated in the invention can be used to treat, ameliorate, and/or prevent cancer in a patient.

HETEROCYCLIC AMIDES AS KINASE INHIBITORS

Disclosed are compounds having the formula (I) wherein X, Y, Z1, Z2, Z3, Z4, R5, RA, m, A. L, and B are as defined herein, and methods of making and using the same.

TRICYCLIC SPIRO-OXINDOLE DERIVATIVES AND THEIR USES AS THERAPEUTIC AGENTS

This invention is directed to tricyclic spiro-oxindole derivatives of formula (I), wherein j, k, m, n, w, q, Y, Q, X, R1, R2 and R3 are as defined herein, as a stereoisomer, enantiomer, tautomer thereof or mixtures thereof; or a pharmaceutically acceptable salt, solvate or prodrug thereof, which are useful for the treatment and/or prevention of sodium channel-mediated diseases or conditions, such as pain. Pharmaceutical compositions comprising the compounds and methods of preparing and using the compounds are also disclosed.