885972-01-0

Upstream product

• 885972-21-4 (S)-1-((E)-But-2-enyl)-5-[(2R,3R)-5-hydroxy-2-((E)-styryl)-tetrahydro-furan-3-yl]-pyrrolidin-2-one 
• 885971-87-9 (S)-1-((E)-But-2-enyl)-5-((E)-(1S,2R)-1-hydroxymethyl-4-phenyl-2-triethylsilanyloxy-but-3-enyl)-pyrrolidin-2-one 
• 885972-14-5 (S)-1-((E)-But-2-enyl)-5-[(E)-(1R,2R)-1-((E)-2-methoxy-vinyl)-4-phenyl-2-triethylsilanyloxy-but-3-enyl]-pyrrolidin-2-one 
• 885971-94-8 (E)-(2R,3R)-2-[(S)-1-((E)-But-2-enyl)-5-oxo-pyrrolidin-2-yl]-5-phenyl-3-triethylsilanyloxy-pent-4-enal 
• 885971-66-4 (-)-5(S)-2[2-(4(R)-phenyl-2-thioxo-thiazolidine-3-yl)-2-oxo-ethyl]-1-(but-2-enyl)-pyrrolidine-2-one 
• 885971-59-5 5-acetoxy N-crotyl pyyrolidine-2-one 

Downstream Products

• 794528-61-3 (1S,3aR,10aS,10bR)-1-methyloctahydro-2H-furo[3,2-c]pyrrolo[1,2-a]azepine-2,8(1H)-dione 

Relevant academic research and scientific papers

Synthesis of (-)-stemoamide using a stereoselective anti-aldol step

The synthesis of (-)-stemoamide was achieved in 11 steps from 5-acetoxy-N-crotyl pyrrolidinone. A chiral N-acyl thiazolidinethione was employed in a stereoselective addition to a cyclic N-acyl iminium ion to install the required stereochemistry of carbon