88609-05-6

Usage

Chemical class

Triazadienes

Explanation

The compound belongs to the class of triazadienes, which are organic compounds containing a triaza-1,2-dien-2-ium group.

Explanation

The compound has a complex structure consisting of a triaza-1,2-dien-2-ium group, a phenyl ring, a sulfamoyl group, and a pyrimidine ring.

Explanation

The compound contains several functional groups, including a triaza-1,2-dien-2-ium group, a phenyl ring, a sulfamoyl group, and a pyrimidine ring.

Explanation

The chemical structure of the compound suggests that it may have potential applications in the pharmaceutical industry, particularly in the development of drugs targeting specific enzymes or receptors.

Explanation

More research is needed to fully understand the properties and potential uses of 1-{4-[(4-methylpyrimidin-2-yl)sulfamoyl]phenyl}triaza-1,2-dien-2-ium, as its current understanding is limited.

Explanation

The compound has a 4-methylpyrimidin-2-yl group attached to the sulfamoyl group and a phenyl ring attached to the triaza-1,2-dien-2-ium group.

Explanation

The triaza-1,2-dien-2-ium group in the compound carries a positive charge of 1+.

Explanation

The compound contains a sulfamoyl group, which is a derivative of a sulfonamide.

Explanation

The phenyl and pyrimidine rings in the compound are aromatic, meaning they have a planar structure and exhibit resonance stabilization.

Explanation

The solubility of the compound in various solvents is not provided in the material and would require further investigation.

Structure

1-4-[(4-methylpyrimidin-2-yl)sulfamoyl]phenyltriaza-1,2-dien-2-ium

Functional groups

Triaza-1,2-dien-2-ium, phenyl, sulfamoyl, and pyrimidine

Potential applications

Pharmaceuticals

Research status

Further research necessary

Substituents

4-methylpyrimidin-2-yl and phenyl

Charge

1+ (triaza-1,2-dien-2-ium)

Sulfonamide derivative

Yes

Aromaticity

Present

Solubility

Unknown

Upstream product

• 127-79-7 sulfamerazina 

Relevant academic research and scientific papers

A Click Synthesis, Molecular Docking, Cytotoxicity on Breast Cancer (MDA-MB 231) and Anti-HIV Activities of New 1,4-Disubstituted-1,2,3-Triazole Thymine Derivatives

Abstract: A new series of 1,4-disubstituted-1,2,3-triazolethymine derivatives (VIa–e) were synthesized and characterized by spectroscopic studies. The in vitro cytotoxic activities of selected compounds against human cancer cell line (MDA-MB 231) were eva

Binding of triazole-linked galactosyl arylsulfonamides to galectin-3 affects Trypanosoma cruzi cell invasion

The synthesis of the O-3 triazole-linked galactosyl arylsulfonamides 1–7 as potential inhibitors of Trypanosoma cruzi cell invasion is described. These target compounds were synthesized by Cu(I)-catalysed azide-alkyne cycloaddition reaction (‘click chemis

Synthesis and in vitro evaluation of novel galactosyl-triazolo-benzenesulfonamides against Trypanosoma cruzi

The only drugs approved for the treatment of Chagas disease, nifurtimox and benznidazole, present toxic side effects and limited efficacy in the chronic stage of the disease, which highlight the need for new drugs. Amongst the different molecular drug tar

Ring-expansion of Azidobenzenesulphonamides and Azidobenzamides

4-Azidobenzenesulphonamides and 2- and 4-azidobenzamides undergo phototransformation to 2-alkoxy-3H-azepines in alcohols but the yields are low.Ring-expansion of 4-azidobenzenesulphonamide and 4-azidobenzenesulphonylguanidine in aqueous tetrahydrofuran to 3H-azepin-2(1H)-ones proceeds via a singlet nitrene pathway; thermolysis of 4-azidobenzenesulphonamide in aqueous dioxane gave only the triplet-derived product, sulphanilamide.Efficient de-azidation of 4-azidobenzesulphonamides and 4-azidobenzamides can be accomplished by heating the azides at 105 deg C in hydrazine hy drate.The crystallographic analysis of 5-sulphamoyl-3H-azepin-2(1H)-one shows the molecule to be non-planar with the azepine ring puckered in a boat form.The lactam configuration is confirmed with the carbonyl group having a bond length of 1.231 Angstroem.