88635-40-9

Upstream product

• 52462-29-0 [ruthenium(II)(η⁶-1-methyl-4-isopropyl-benzene)(chloride)(μ-chloride)]₂ 
• 2071-20-7 bis-diphenylphosphinomethane 

Downstream Products

• 599199-20-9 [(η6-p-cymene)(η2-bis(diphenylphosphino)methane)RuCl]Cl 
• 240803-86-5 [(η(6)-cymene)RuCl2(η(1)-Ph2PCH2P(O)Ph2)] 
• 88611-20-5 C₄₅H₅₀Cl₄P₂Ru₂ 

Relevant academic research and scientific papers

Facile entry to germanate and stannate complexes [(η6-arene)RuCl(η2-dppm)]+[ECl3]- (E = Ge, Sn) as potent anti-cancer agents

A series of arene Ru(II) salt complexes of the type [(η6-arene)RuCl(η2-dppm)]+[ECl3]- (arene = C6H6, p-cymene, 1,3,5-Me3C6H3; E = Ge, Sn) bearing

Synthesis, X-ray structure of organometallic ruthenium (II) p-cymene complexes based on P- and N- donor ligands and their in?vitro antibacterial and anticancer studies

Two new arene compounds containing bis-diphosphinomethane (dppm) and tert-butylpyridine (tbp) ligands as important components in ruthenium(II) complexes were synthesized and characterized by X-ray crystallography, and spectroscopy of 1H NMR, s

Design, synthesis and characterisation of new chimeric ruthenium(ii)-gold(i) complexes as improved cytotoxic agents

Two heterobimetallic complexes, i.e. [RuCl2(p-cymene)(μ-dppm)AuC] (1) and [RuCl2(p-cymene)(μ-dppm)Au(S-thiazoline)] (3), based on known cytotoxic [Ru(p-cymene)Cl2(PR3)] and [AuX(PR3)] (X = Cl, SR) mol

Mechanistic studies on the formation of η2-diphosphine (η6-p-cymene)ruthenium(II) compounds

A new range of pendent diphosphine (η6-p-cymene) ruthenium(II) complexes, [RuCl(PPh3)(η1-(P-P))- (η6-p-cymene)]PF6 (P-P -dppm, cis-PPh 2CHCHPPh2 (dppv), dppe, dppp, dppf), have been prepared by substitution of the labile acetonitrile ligand in [RuCl(CH3CN) (PPh3)(η6-p-cymene)]PF6. The formation of chelate complexes, [RuCl(η2-(P-P))(η6-p-cymene)] +, from these pendent phosphine complexes and from the related neutral complexes, [RuCl2(η1-(P-P))(η6- p-cymene)] (P-P = dppm, dppv), has been investigated, including determination of activation enthalpies (ΔH?) and entropies (ΔS?). A concerted substitution mechanism is proposed for the latter complexes, in which methanol plays an important role in the ring-closing process by formation of hydrogen bonds with the chloride ligands. This proposal is supported by volumes of activation (ΔV?) determined by variable-pressure UV-visible spectroscopy. In contrast, a dissociative mechanism is proposed for the series of cationic pendent phosphine complexes, which generally require higher temperatures to effect ring closure. Secondary reaction pathways can be observed in some cases and are discussed in terms of differences between the phosphine complexes and supplemented by investigations using electrospray ionization mass spectrometry (ESI-MS). The X-ray structures of [RuCl(PPh3) (η1-(P-P))(η6-p-cymene)]PF6 (P-P = dppm, dppv, dppp) and [RuCl(η2-dppv)-(η6-p-cymene) ]PF6 are also reported.

Dehalogenation of binuclear arene-ruthenium complexes: A new route to homonuclear triruthenium and heteronuclear ruthenium-iron cluster complexes containing chelating phosphorus ligands. Crystal structure of Ru3(CO)10(Ph2PCH2PPh2)

The binuclear complexes (RuCl2(p-cymene))2(Ph2P(CH2) nPPh2) (2, n = 2; 4, n = 1) obtained from (RuCl2(p-cymene))2 have been reacted with an excess of Fe2(CO)9. The former derivative, 2, yielded FeRu(CO)8(Ph2PCH2CH2PPh2) (5), (Fe2Ru(μ-CO)2(CO)9)2(Ph 2PCH2CH2PPh2) (6), Ru3(μ-Cl)2(CO)8(Ph2PCH 2CH2PPh2) (7), and FeRu2(μ-Cl)2(CO)8(Ph2PCH 2CH2PPh2) (8) (noticeably, thermolysis of 8 under mild conditions yielded 7). The latter derivative, 4, afforded Ru3(CO)10(Ph2PCH2PPh2) (9) and FeRu2(CO)10(Ph2PCH2PPh2) (10). The X-ray crystal structure of 9 has been determined: monoclinic crystals, space group P21/c with a = 13.122 (3) A?, b = 12.040 (4) A?, c = 23.658 (7) A?, β = 103.44 (2)°, and Z = 4. Final R and Rw values are respectively 0.036 and 0.041 on the basis of 4346 independent reflections. The Ph2PCH2PPh2 group that bridges a Ru-Ru bond occupies equatorial positions. Interatomic distances of interest are Ru(1)-Ru(2) = 2.834 (1), Ru(1)-Ru(3) = 2.841 (1), and Ru(2)-Ru(3) = 2.860 (1) A?. The shortest bond Ru(1)-Ru(2) is supported by the chelating phosphorus ligand (Ru(1)-P(1) = 2.322 (2) and Ru(2)-P(2) = 2.334 (2) A?). Ru-P bonds are not coplanar as shown by the dihedral angle P(1)-Ru(1)-Ru(2)/P(2)-Ru(2)-Ru(1) = 19.1 (1)°. Such a distortion induces a disturbance in the distribution of CO ligands with respect to Ru3(CO)12. Of particular interest is the bending of every axial carbonyl toward one Ru-Ru bond.