886361-30-4

Basic information

• Product Name: METHYL 2-AMINO-5-(4-FLUOROPHENYL)-1,3-THIAZOLE-4-CARBOXYLATE
• Synonyms: METHYL 2-AMINO-5-(4-FLUOROPHENYL)-1,3-THIAZOLE-4-CARBOXYLATE;5-(4-Fluorophenyl)-4-(methoxycarbonyl)-1,3-thiazol-2-amine;10X-0996;2-amino-5-(4-fluorophenyl)-4-thiazolecarboxylic acid methyl ester;2-amino-5-(4-fluorophenyl)thiazole-4-carboxylic acid methyl ester;methyl 2-amino-5-(4-fluorophenyl)thiazole-4-carboxylate;ZINC03883305
• CAS NO: 886361-30-4
• Molecular Formula: C₁₁H₉FN₂O₂S
• Molecular Weight: 252.26
• Product Categories: Thiazoles, Isothiazoles &Benzothiazoles;Esters;Thiazoles, Isothiazoles & Benzothiazoles
• Mol File: 886361-30-4.mol
• Article Data: 12

Chemical Properties

• Melting Point: 202
• Boiling Point: 438.6±35.0 °C(Predicted)
• Appearance: /
• Density: 1.387±0.06 g/cm3(Predicted)
• PKA: 1.99±0.10(Predicted)
• CAS DataBase Reference: METHYL 2-AMINO-5-(4-FLUOROPHENYL)-1,3-THIAZOLE-4-CARBOXYLATE(CAS DataBase Reference)
• NIST Chemistry Reference: METHYL 2-AMINO-5-(4-FLUOROPHENYL)-1,3-THIAZOLE-4-CARBOXYLATE(886361-30-4)
• EPA Substance Registry System: METHYL 2-AMINO-5-(4-FLUOROPHENYL)-1,3-THIAZOLE-4-CARBOXYLATE(886361-30-4)

Safety Data

• Hazard Codes: Xi
• HazardClass: IRRITANT
• Hazardous Substances Data: 886361-30-4(Hazardous Substances Data)

Upstream product

• 160727-95-7 methyl 3-chloro-3-(4-fluorophenyl)-2-oxopropanoate 
• 17356-08-0 thiourea 

Downstream Products

• 1038508-94-9 2-bromo-5-(4-fluoro-phenyl)-thiazole-4-carboxylic acid methyl ester 
• 1038508-87-0 2-cyclopropyl-5-(4-fluoro-phenyl)-thiazole-4-carboxylic acid methyl ester 
• 1422175-27-6 C₁₁H₉FN₂O₄S₂ 
• 1422176-17-7 C₁₂H₁₁FN₂O₄S₂ 

Relevant articles and documents

2-AZA-BICYCLO[3.3.0]OCTANE DERIVATIVES

The invention relates to 2-aza-bicyclo[3.3.0]octane derivatives of Formula (I) wherein A, B, and R1 are as described in the description, and to the use of such compounds, or of pharmaceutically acceptable salts of such compounds, as medicaments, especially as orexin receptor antagonists.

1,2-DIAMIDO-ETHYLENE DERIVATIVES AS OREXIN ANTAGONISTS

The invention relates to 1,2-diamido-ethylene derivatives of the formula (I) wherein R1, R2, R3, and A are as described in the description and their use as medicaments, especially as orexin receptor antagonists.

OXAZOLIDINE COMPOUNDS AS OREXIN RECEPTOR ANTAGONISTS

The invention relates to oxazolidine derivatives of the formula (I) wherein A, B, and R1 are as described in the description, to salts, especially pharmaceutically acceptable salts, of such compounds and to their use as medicaments, especially