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Methyl 3-bromoH-imidazo[1,2-a]pyridine-6-carboxylate is a heterocyclic chemical compound characterized by a unique fused ring system, a bromo group, and a carboxylate functional group. With the molecular formula C9H7BrN2O2, methyl 3-bromoH-imidazo[1,2-a]pyridine-6-carboxylate holds potential in the realm of medicinal chemistry and drug discovery, serving as a valuable building block for the synthesis of biologically active molecules. Its distinctive structure and reactivity contribute to its utility as an intermediate in the creation of pharmaceuticals and agrochemicals, while also positioning it as a promising candidate for further research in developing novel pharmaceutical compounds and materials.

886361-98-4

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886361-98-4 Usage

Uses

Used in Medicinal Chemistry:
Methyl 3-bromoH-imidazo[1,2-a]pyridine-6-carboxylate is utilized as a key intermediate in the synthesis of pharmaceuticals, leveraging its unique structure and reactivity to contribute to the development of new drugs with enhanced therapeutic properties.
Used in Drug Discovery:
As a building block in drug discovery, methyl 3-bromoH-imidazo[1,2-a]pyridine-6-carboxylate aids in the creation of biologically active molecules, which can be further optimized for specific therapeutic targets, thereby expanding the range of available treatments for various diseases and conditions.
Used in Agrochemicals:
In the agrochemical industry, methyl 3-bromoH-imidazo[1,2-a]pyridine-6-carboxylate is employed as a precursor in the synthesis of agrochemicals, potentially leading to the development of new pesticides or other agricultural products that can improve crop yields and protect against pests.
Used in Research and Development:
Methyl 3-bromoH-imidazo[1,2-a]pyridine-6-carboxylate serves as a promising candidate for research in the development of new pharmaceutical compounds and materials, driving innovation in the field of medicinal chemistry and contributing to the advancement of healthcare and agriculture.

Check Digit Verification of cas no

The CAS Registry Mumber 886361-98-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,8,6,3,6 and 1 respectively; the second part has 2 digits, 9 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 886361-98:
(8*8)+(7*8)+(6*6)+(5*3)+(4*6)+(3*1)+(2*9)+(1*8)=224
224 % 10 = 4
So 886361-98-4 is a valid CAS Registry Number.

886361-98-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name Methyl 3-bromoimidazo[1,2-a]pyridine-6-carboxylate

1.2 Other means of identification

Product number -
Other names 3-bromo-imidazo[1,2-a]pyridine-6-carboxylic acid methyl ester

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:886361-98-4 SDS

886361-98-4Relevant academic research and scientific papers

Lead optimization of imidazopyrazines: A new class of antimalarial with activity on Plasmodium liver stages

Zou, Bin,Nagle, Advait,Chatterjee, Arnab K.,Leong, Seh Yong,Tan, Liying Jocelyn,Sim, Wei Lin Sandra,Mishra, Pranab,Guntapalli, Prasuna,Tully, David C.,Lakshminarayana, Suresh B.,Lim, Chek Shik,Tan, Yong Cheng,Abas, Siti Nurdiana,Bodenreider, Christophe,Kuhen, Kelli L.,Gagaring, Kerstin,Borboa, Rachel,Chang, Jonathan,Li, Chun,Hollenbeck, Thomas,Tuntland, Tove,Zeeman, Anne-Marie,Kocken, Clemens H. M.,McNamara, Case,Kato, Nobutaka,Winzeler, Elizabeth A.,Yeung, Bryan K. S.,Diagana, Thierry T.,Smith, Paul W.,Roland, Jason

supporting information, p. 947 - 950 (2014/10/15)

Imidazopyridine 1 was identified from a phenotypic screen against P. falciparum (Pf) blood stages and subsequently optimized for activity on liver-stage schizonts of the rodent parasite P. yoelii (Py) as well as hypnozoites of the simian parasite P. cynomolgi (Pc). We applied these various assays to the cell-based lead optimization of the imidazopyrazines, exemplified by 3 (KAI407), and show that optimized compounds within the series with improved pharmacokinetic properties achieve causal prophylactic activity in vivo and may have the potential to target the dormant stages of P. vivax malaria.

ORGANIC COMPOUNDS

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Page/Page column 122, (2009/05/28)

Compounds of formula (I): in free or salt or solvate form, where R1, R2, R3 and R20 have the meanings as indicated in the specification, are useful for treati ng diseases mediated by the ALK-5 and/or ALK-4 receptor. Pharmaceutical composit ions that contain the compounds and processes for preparing the compounds are also described.

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