886366-17-2

Basic information

• Product Name: (5-BROMO-PYRIMIDIN-2-YL)-CYCLOHEXYL-AMINE
• Synonyms: (5-BROMO-PYRIMIDIN-2-YL)-CYCLOHEXYL-AMINE;5-BROMO-N-CYCLOHEXYLPYRIMIDIN-2-AMINE;5-Bromo-2-cyclohexylaminopyrimidine
• CAS NO: 886366-17-2
• Molecular Formula: C₁₀H₁₄BrN₃
• Molecular Weight: 256.14
• Mol File: 886366-17-2.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: (5-BROMO-PYRIMIDIN-2-YL)-CYCLOHEXYL-AMINE(CAS DataBase Reference)
• NIST Chemistry Reference: (5-BROMO-PYRIMIDIN-2-YL)-CYCLOHEXYL-AMINE(886366-17-2)
• EPA Substance Registry System: (5-BROMO-PYRIMIDIN-2-YL)-CYCLOHEXYL-AMINE(886366-17-2)

Safety Data

• Hazard Codes: Xn
• Statements: 22
• Hazardous Substances Data: 886366-17-2(Hazardous Substances Data)

Usage

Description

(5-BROMO-PYRIMIDIN-2-YL)-CYCLOHEXYL-AMINE is a chemical compound characterized by the presence of a pyrimidine ring with a bromine atom substitution and a cyclohexyl-amine group. It is recognized for its significance in the pharmaceutical and agricultural sectors, primarily serving as an intermediate in the synthesis of a variety of drugs and agrochemicals. This versatile compound is also valued as a research reagent in chemical and medicinal studies, owing to its adaptable chemical properties, and plays a crucial role as a building block in the creation of bioactive molecules for medicinal chemistry.

Uses

Used in Pharmaceutical Industry:
(5-BROMO-PYRIMIDIN-2-YL)-CYCLOHEXYL-AMINE is used as an intermediate compound for the synthesis of various pharmaceuticals, contributing to the development of potential drug candidates for a range of therapeutic applications. Its unique structure allows for the creation of new molecules with specific biological activities, making it a valuable asset in drug discovery and medicinal chemistry.
Used in Agricultural Industry:
In the agricultural sector, (5-BROMO-PYRIMIDIN-2-YL)-CYCLOHEXYL-AMINE is utilized as an intermediate in the production of agrochemicals, aiding in the development of effective and targeted pest control solutions. Its role in the synthesis of agrochemicals helps to enhance crop protection and contribute to sustainable agricultural practices.
Used as a Research Reagent:
(5-BROMO-PYRIMIDIN-2-YL)-CYCLOHEXYL-AMINE is employed as a research reagent in chemical and medicinal studies, where its versatile chemical properties facilitate investigations into new chemical reactions, synthesis pathways, and the exploration of its potential biological activities. This application supports the advancement of knowledge in chemistry and medicine, fostering innovation in drug and agrochemical development.

Upstream product

• 108-91-8 cyclohexylamine 
• 32779-36-5 5-Bromo-2-chloropyrimidine 

Downstream Products

• 1407999-92-1 C₃₃H₃₈F₃N₉O 
• 1257628-65-1 3-(2-(2-(cyclohexylamino)pyrimidin-5-yl)ethynyl)-4-methyl-N-(3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)benzamide 
• 1408000-37-2 N-cyclohexyl-5-ethynylpyrimidin-2-amine 
• 1581701-24-7 C₁₂H₁₇N₃O₂ 
• 1215560-20-5 C₁₁H₁₅N₃O₂ 
• 1581701-31-6 2-(cyclohexylamino)-N-(2-methyl-5-((4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)carbamoyl)phenyl)pyrimidine-5-carboxamide 

Relevant articles and documents

Heterocyclic benzoyl amide compounds, medicinal composition and use thereof

The invention discloses heterocyclic benzamide compounds with structural characteristics of formula (1) or pharmaceutically acceptable salts or steric isomers or prodrug molecules thereof. The heterocyclic benzamide compounds as well as pharmaceutically acceptable salts thereof can effectively restrain growth of a plurality of tumor cells, can generate inhibiting effect to proteases such as BCR-ABL, c-Kit and PDGFR, can be used for preparing anti-tumor drugs and can be used for overcoming existing drug (Gleevec)-induced drug resistance.