886373-28-0

Basic information

• Product Name: 5-BROMO-3-FLUORO-PYRIDINE-2-CARBONITRILE
• Synonyms: 5-bromo-3-fluoropicolinonitrile;5--3-·ú-2-áà¤×;5-BroMo-2-cyano-3-fluorop...;5-BroMo-2-cyano-3-fluoropyridine;5-Bromo-2-cyano-3-fluoropyridine, 5-Bromo-3-fluoropicolinonitrile;5-BroMo-3-fluoro-2-pyridinecarbonitrile;5-BROMO-3-FLUORO-PYRIDINE-2-CARBONITRILE;2-Pyridinecarbonitrile, 5-bromo-3-fluoro-
• CAS NO: 886373-28-0
• Molecular Formula: C₆H₂BrFN₂
• Molecular Weight: 200.9958832
• EINECS: 1533716-785-6
• Product Categories: Heterocyclic Building Blocks
• Mol File: 886373-28-0.mol
• Article Data: 12

Chemical Properties

• Melting Point: 103-105℃
• Boiling Point: 238.0±35.0℃ (760 Torr)
• Flash Point: 97.7±25.9℃
• Appearance: /
• Density: 1.81±0.1 g/cm3 (20 ºC 760 Torr)
• Vapor Pressure: 0.0435mmHg at 25°C
• Refractive Index: 1.58
• Storage Temp.: ?20°C
• PKA: -5.10±0.20(Predicted)
• CAS DataBase Reference: 5-BROMO-3-FLUORO-PYRIDINE-2-CARBONITRILE(CAS DataBase Reference)
• NIST Chemistry Reference: 5-BROMO-3-FLUORO-PYRIDINE-2-CARBONITRILE(886373-28-0)
• EPA Substance Registry System: 5-BROMO-3-FLUORO-PYRIDINE-2-CARBONITRILE(886373-28-0)

Safety Data

• Hazard Codes: Xn
• Statements: 22-38-41
• Safety Statements: 26-39
• RIDADR: UN 2811 6.1 / PGIII
• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 886373-28-0(Hazardous Substances Data)

Usage

General Description

5-Bromo-3-fluoro-pyridine-2-carbonitrile is a chemical compound with the molecular formula C6H2BrFN2. It is a pyridine derivative with a bromine and a fluorine atom attached to the 3 and 5 positions of the pyridine ring, respectively, and a cyano group attached to the 2 position. 5-Bromo-3-fluoro-pyridine-2-carbonitrile is used in the synthesis of pharmaceuticals and agrochemicals, as well as in the development of new materials and compounds. It has potential applications in the field of medicinal chemistry and drug discovery due to its unique chemical structure and properties. Additionally, it may also be used as a building block for the synthesis of various other organic compounds.

InChI:InChI=1/C6H2BrFN2/c7-4-1-5(8)6(2-9)10-3-4/h1,3H

Upstream product

• 573675-25-9 5-bromo-3-nitropyridine-2-carbonitrile 
• 15862-37-0 2,5-dibromo-3-nitro-pyridine 
• 15862-34-7 5-bromo-3-nitro-2-pyridone 
• 669066-90-4 5-bromo-3-fluoro-pyridine-2-carboxylic acid amide 

Downstream Products

• 1211538-72-5 methyl 5-bromo-3-fluoro-pyridine-2-carboxylate 
• 1256836-96-0 methyl 3-fluoro-5-hydroxypyridine-2-carboxylate 
• 1206968-92-4 (5-bromo-3-fluoropyridin-2-yl)methanol 
• 1160936-52-6 1-(5-bromo-3-fluoropyridin-2-yl)ethan-1-one 

Relevant articles and documents

COMPOUNDS AND COMPOSITIONS FOR USE IN TREATING SKIN DISORDERS

Provided herein is a compound of formula (XXXII) or a pharmaceutically acceptable salt, solvate, hydrate, stereoisomer thereof or a physiologically functional derivative thereof, wherein R1, R2, R3, G, A, E, n, p, and q are defined herein. Also provided herein are compositions comprising a compound of formula (XXXII), and methods of using a compound of formula (XXXII), e.g., in the treatment or prevention of skin disorders.

NEW BIARYL AMIDE DERIVATIVES

The invention provides novel compounds having the general formula (I) wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11, R12 and A are as described herein, compositions including the compounds and methods of using the compounds.

3-(BIARYLOXY) PROPIONIC ACID DERIVATIVE

A compound of the general formula (I): [wherein, R1 represents a halogen atom, or the like, R2 represents a hydrogen atom, or the like, R3 and R4, each independently, represent a hydrogen atom, a C1-4