886435-01-4 Usage
Uses
Used in Organic Synthesis:
[2,2'-Binaphthalene]-1,1',4,4'-tetrone, 6,6',7,7'-tetrakis(acetyloxy)-1,1',4,4'-tetrahydro-3,3'-diMethyl-5,5'-bis(1-Methylethyl)is used as a key intermediate in organic synthesis for the creation of various complex molecules. Its unique structure and functional groups allow for a wide range of reactions and modifications, making it a valuable compound in this field.
Used in Pharmaceutical Production:
In the pharmaceutical industry, [2,2'-Binaphthalene]-1,1',4,4'-tetrone, 6,6',7,7'-tetrakis(acetyloxy)-1,1',4,4'-tetrahydro-3,3'-diMethyl-5,5'-bis(1-Methylethyl)is used as a building block for the development of new drugs. Its structural diversity and functional groups enable the design of molecules with specific biological activities, targeting various medical conditions.
Used in Material Production:
[2,2'-Binaphthalene]-1,1',4,4'-tetrone, 6,6',7,7'-tetrakis(acetyloxy)-1,1',4,4'-tetrahydro-3,3'-diMethyl-5,5'-bis(1-Methylethyl)also finds application in the production of advanced materials. Its unique properties can be utilized to create materials with specific characteristics, such as improved mechanical strength, thermal stability, or chemical resistance, depending on the desired application.
Check Digit Verification of cas no
The CAS Registry Mumber 886435-01-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,8,6,4,3 and 5 respectively; the second part has 2 digits, 0 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 886435-01:
(8*8)+(7*8)+(6*6)+(5*4)+(4*3)+(3*5)+(2*0)+(1*1)=204
204 % 10 = 4
So 886435-01-4 is a valid CAS Registry Number.
886435-01-4Relevant academic research and scientific papers
Design and synthesis of a gossypol derivative with improved antitumor activities
Zhan, Yonghua,Jia, Guangfeng,Wu, Daocheng,Xu, Yiqing,Xu, Liang
experimental part, p. 223 - 229 (2009/05/26)
A novel chemical process has been devised for the synthesis of a new derivative of gossypol, 6,7,6',7'-tetrahydroxy-5,5'-diisopropyl-3,3'-dimethyl- [2,2']binaphthalenyl-1,4,1',4'-tetraone (Apogossypolone). This new process has only four steps, with a shorter synthesis span, a simple purification process, and improved yield and quality. The structure of apogossypolone was characterized by 1H-nuclear magnetic resonance, 13C- nuclear magnetic resonance, mass spectroscopy, infrared spectroscopy, and elemental analysis. Cell-cytotoxicity assay demonstrates that apogossypolone is three- to six-fold more potent than the parent compound, (-)-gossypol, in inhibiting the human prostate tumor cell lines PC-3 and DU-145 as well as the human breast cancer cell line MDA-MB-231. The colony-formation assay with DU-145 cells showed that apogossypolone inhibited more than 70% of colony formation at 1 μM, whereas (-)-gossypol at 10 μM only inhibited less than 50% of colony formation. The results indicate that apogossypolone exerts strong antitumor activities in human prostate and breast cancer cells, and thus represents a promising cancer therapeutic.
