88647-16-9Relevant academic research and scientific papers
SYNTHESIS OF 3-(1-ALKENYLOXY)-1,2-PROPANEDIOLS, ENOL ETHERS OF GLYCEROL, BY THE HORNER-WITTIG REACTION.
Schaik, T. A. M. van,Gen, A. van der
, p. 465 - 466 (2007/10/02)
Reaction of the anion derived from phosphine oxide 4 with saturated and unsaturated aldehydes provides diastereomeric mixtures of the adducts 5.After removal of the protecting group these can be separated and, upon reaction with base, afford the pure E- and Z-isomers of glyceryl enol ethers 7 in good yields.
