886508-80-1 Usage
General Description
5-(2-Fluoro-phenyl)-thiophene-2-carbaldehyde is a chemical compound with the molecular formula C12H7FOS. It is a derivative of thiophene and contains a fluorophenyl group and a carbaldehyde functional group. This chemical is commonly used in the synthesis of various organic compounds and pharmaceuticals. It is also known for its aromatic and benzene-like odor. Additionally, 5-(2-Fluoro-phenyl)-thiophene-2-carbaldehyde has been studied for its potential applications in materials science and medicinal chemistry. Overall, it is a versatile compound with a wide range of uses in organic synthesis and research.
Check Digit Verification of cas no
The CAS Registry Mumber 886508-80-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,8,6,5,0 and 8 respectively; the second part has 2 digits, 8 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 886508-80:
(8*8)+(7*8)+(6*6)+(5*5)+(4*0)+(3*8)+(2*8)+(1*0)=221
221 % 10 = 1
So 886508-80-1 is a valid CAS Registry Number.
886508-80-1Relevant articles and documents
Inhibitors of HCV NS5B polymerase. Part 1: Evaluation of the southern region of (2Z)-2-(benzoylamino)-3-(5-phenyl-2-furyl)acrylic acid
Pfefferkorn, Jeffrey A.,Greene, Meredith L.,Nugent, Richard A.,Gross, Rebecca J.,Mitchell, Mark A.,Finzel, Barry C.,Harris, Melissa S.,Wells, Peter A.,Shelly, John A.,Anstadt, Robert A.,Kilkuskie, Robert E.,Kopta, Laurice A.,Schwende, Francis J.
, p. 2481 - 2486 (2007/10/03)
A novel series of nonnucleoside HCV NS5B polymerase inhibitors were prepared from (2Z)-2-(benzoylamino)-3-(5-phenyl-2-furyl)acrylic acid, a high throughput screening lead. SAR studies combined with structure based drug design focusing on the southern heterobiaryl region of the template led to the synthesis of several potent and orally bioavailable lead compounds. X-ray crystallography studies were also performed to understand the interaction of these inhibitors with HCV NS5B polymerase.
