886593-61-9

Basic information

• Product Name: 4-bromo-2-(2-oxoethyl)benzonitrile
• Synonyms: 4-bromo-2-(2-oxoethyl)benzonitrile
• CAS NO: 886593-61-9
• Molecular Weight: 224.057
• Mol File: 886593-61-9.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: 4-bromo-2-(2-oxoethyl)benzonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 4-bromo-2-(2-oxoethyl)benzonitrile(886593-61-9)
• EPA Substance Registry System: 4-bromo-2-(2-oxoethyl)benzonitrile(886593-61-9)

Safety Data

• Hazardous Substances Data: 886593-61-9(Hazardous Substances Data)

Upstream product

• 67832-11-5 4-bromo-2-methylbenzonitrile 
• 1220229-19-5 (E)-4-bromo-2-(2-(dimethylamino)vinyl)benzonitrile 
• 68-12-2 N,N-dimethyl-formamide 
• 886593-62-0 4-bromo-2-(2-dimethylaminovinyl)benzonitrile 

Downstream Products

• 1162262-43-2 6-bromo-3,4-dihydro-1H-isochromen-1-one 
• 886592-93-4 4-bromo-2-(2-{2-[2-(4-methylpiperazin-1-yl)-phenyl]ethylamino}-ethyl)benzonitrile 

Relevant articles and documents

CONDENSED BI-HETEROCYCLES AS INHIBITING AGENTS FOR BRUTON'S TYROSINE KINASE

Provided are compounds of Formula (I): Formula (I) or pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R4, R5, R6, A1, B1, B2, Q1 and Q2 are as defined herein; and methods for their use and production.

BIARYL COMPOUNDS USEFUL FOR THE TREATMENT OF HUMAN DISEASES IN ONCOLOGY, NEUROLOGY AND IMMUNOLOGY

The present invention provides compounds and compositions thereof which are useful as inhibitors of Bruton's tyrosine kinase and which exhibit desirable characteristics for the same.

INHIBITORS OF THE RENAL OUTER MEDULLARY POTASSIUM CHANNEL

The present invention provides compounds of Formula (I) and the pharmaceutically acceptable salts thereof, which are inhibitors of the ROMK (Kir1.1) channel. The compounds act as diuretics and natriuretics and are valuable pharmaceutically active compounds for the therapy and prophylaxis of medical conditions including cardiovascular diseases such as hypertension and conditions resulting from excessive salt and water retention.