886762-35-2 Usage
Uses
Used in Organic Synthesis:
1-Iodo-2-nitro-4-(trifluoromethoxy)benzene serves as a building block and an essential component in organic synthesis, contributing to the creation of a broad range of chemical products.
Used in Pharmaceutical and Agrochemical Industries:
As a key intermediate, 1-Iodo-2-nitro-4-(trifluoromethoxy)benzene is used in the development and production of various pharmaceuticals and agrochemicals, highlighting its significance in these industries.
Used in Dye and Pigment Production:
Leveraging its aromatic characteristics, 1-Iodo-2-nitro-4-(trifluoromethoxy)benzene is employed as a precursor in the manufacturing of dyes, pigments, and other aromatic chemicals, which are vital for coloring various materials and products.
Used in Electronic Materials Manufacturing:
1-Iodo-2-nitro-4-(trifluoromethoxy)benzene also finds application in the production of electronic materials, where its unique properties contribute to the development of advanced technologies.
Used in Synthesis of Other Organic Compounds:
1-Iodo-2-nitro-4-(trifluoromethoxy)benzene acts as an intermediate in the synthesis of other organic compounds, further expanding its utility in the chemical industry.
Used in Medicinal Chemistry for Antifungal and Antibacterial Properties:
1-Iodo-2-nitro-4-(trifluoromethoxy)benzene has been studied for its potential antifungal and antibacterial properties, making it an important substance in medicinal chemistry for developing new treatments and therapies.
Check Digit Verification of cas no
The CAS Registry Mumber 886762-35-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,8,6,7,6 and 2 respectively; the second part has 2 digits, 3 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 886762-35:
(8*8)+(7*8)+(6*6)+(5*7)+(4*6)+(3*2)+(2*3)+(1*5)=232
232 % 10 = 2
So 886762-35-2 is a valid CAS Registry Number.
886762-35-2Relevant academic research and scientific papers
Quinazolinone and isoquinolinone derivative
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Paragraph 0358; 0359, (2016/10/08)
The present invention relates to quinazolinone and isoquinolinone derivatives represented by formula (I) or pharmaceutically acceptable salts thereof.
BENZAMIDE DERIVATIVE
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Paragraph 1549; 1550, (2015/03/16)
The present invention relates to benzamide derivatives represented by formula (I) or pharmaceutically acceptable salts thereof.
Practical, highly convergent, asymmetric synthesis of a selective PPARγ modulator
Maligres, Peter E.,Humphrey, Guy R.,Marcoux, Jean-Francois,Hillier, Michael C.,Zhao, Dalian,Krska, Shane,Grabowski, Edward J.J.
experimental part, p. 525 - 534 (2010/04/22)
A practical, highly convergent, asymmetric synthesis of a selective PPARγ modulator 1 is described. The inhibitor contains two key components, a 6-trifluoromethoxy-3-acylindole (6) and (R)-raryloxybutanoic acid derivative (10). Twomethods were developed to overcome the regioselectivity issues encountered in the preparation of the 6-substituted indole. The first involved an intramolecular Heck reaction of an iodoaryl enamine. The second involved application of a catalytic Meerwein arylation reaction between 2-nitro-4-trifluoromethoxyaniline and isopropenyl acetate and subsequent reductive cyclization. The α-aryloxybutanoic acid was prepared via an asymmetric hydrogenation of the corresponding α-aryloxy-α,β- unsaturated acid. Tetrabutylammonium iodidecatalyzed coupling of the two fragments and ester hydrolysis completed the convergent synthesis. The described convergent synthesis was used to prepare >3 kg of drug substance 1 in 50% overall yield and with >99.5% ee.
