886848-88-0

Basic information

• Product Name: [[Pd[(η(5)-C5H5)Fe(η(5)-C5H4)C(H)=NN=C(S)NH2](Cl)(PPh3)]
• CAS NO: 886848-88-0
• Molecular Weight: 690.324
• Mol File: 886848-88-0.mol

Chemical Properties

• CAS DataBase Reference: [[Pd[(η(5)-C5H5)Fe(η(5)-C5H4)C(H)=NN=C(S)NH2](Cl)(PPh3)](CAS DataBase Reference)
• NIST Chemistry Reference: [[Pd[(η(5)-C5H5)Fe(η(5)-C5H4)C(H)=NN=C(S)NH2](Cl)(PPh3)](886848-88-0)
• EPA Substance Registry System: [[Pd[(η(5)-C5H5)Fe(η(5)-C5H4)C(H)=NN=C(S)NH2](Cl)(PPh3)](886848-88-0)

Safety Data

• Hazardous Substances Data: 886848-88-0(Hazardous Substances Data)

Upstream product

• 1441781-13-0 C₂₄H₂₄Cl₂Fe₂N₆Pd₂S₂ 
• 603-35-0 triphenylphosphine 

Relevant articles and documents

Heterobimetallic ferrocenylthiosemicarbazone palladium(II) complexes: Synthesis, electrochemistry and antiplasmodial evaluation

Heterobimetallic ferrocenylthiosemicarbazone palladium(II) complexes (3-5) were prepared through the cleavage of a chlorido-bridged palladium ferrocenylthiosemicarbazone intermediate (2) using various P-donor ligands. These compounds were screened for antiplasmodial activity against chloroquine-sensitive (NF54) and chloroquine-resistant (Dd2) Plasmodium falciparum strains, exhibiting biological activity in the low micromolar range. The compounds generally display well-resolved electrochemically reversible one-electron transfer processes for the ferrocenyl group. The half-wave potential for the Fe(II)/Fe(III) couple is electronically influenced by the type of P-donor group through the palladium(II) centre.

Synthesis and crystal structure analysis of ferrocenylthiosemicarbazone complexes of palladium(II): Unusual σpd-C bond cleavage

The reaction of the thiosemicarbazones (η5-C 5H5)Fe(η5-C5H 4)C(H)NN(H)C(S)NHR (R = H, a; R = Me, b) with K2PdCl 4 afforded octanuclear cyclometallated complexes [Pd{(η 5-C5H5)Fe(η5-C5H 3)C(H)NNC(S)NHR}]4 (R = H, 1a; R = Me, 1b). Reaction of complexes 1a and 1b with tertiary diphosphines in 1:2 molar ratio and subsequent recrystallization from CH2Cl2/n-C6H 14 gave rise to tetranuclear complexes [{Pd[(η5-C 5H5)Fe(η5-C5H 4)C(H)NNC(S)NHR](Cl)}2(μ-Ph2P(CH 2)nPPh2)] (R = H, n = 4, 2a; R = Me, n = 1, 2b; n = 4, 3b). Treatment of complexes 1a and 1b with tertiary monophosphines in 1:4 molar ratio and subsequent recrystallization from CH2Cl 2/n-C6H14 gave rise to dinuclear complexes [Pd{(η5-C5H5)Fe(η5-C 5H4)C(H)NNC(S)-NHR}(Cl)(P)] (R = H: P = PPh3, 3a; P = PPh2Et, 4a; P = P(C6D5)3, 5a; R = Me: P = PPh3, 4b; P = PPh2Et, 5b; P = P(C 6D5)3, 6b). The crystal structures of 2a and 2b have been determined by X-ray crystallography.