886852-47-7

Upstream product

• 118924-06-4 ethyl 1-thio-α-D-arabinofuranoside 
• 1448225-42-0 ethyl 5-O-tert-butyldiphenylsilyl-1-thio-α-D-arabinofuranoside 
• 100-44-7 benzyl chloride 
• 282107-51-1 Ethyl 2-O-benzoyl-3-O-benzyl-1-thio-α-D-arabinofuranoside 

Downstream Products

• 886852-29-5 ethyl 2,3-di-O-benzyl-5-O-p-methoxybenzyl-1-thio-α-D-arabinofuranoside 
• 1448225-51-1 methyl 2,3-di-O-benzyl-5-O-(2-pyridinecarbonyl)-β-D-arabinofuranosyl-(1→3)-2,5-di-O-benzoyl-α-D-arabinofuranoside 
• 1448225-84-0 C₄₅H₄₃NO₁₂ 
• 1448225-52-2 methyl 2,3-di-O-benzyl-5-O-(2-pyridinecarbonyl)-β-D-arabinofuranosyl-(1→2)-3,5-di-O-benzoyl-α-D-arabinofuranoside 
• 1448225-53-3 methyl 2,3-di-O-benzyl-5-O-(2-pyridinecarbonyl)-α-D-arabinofuranosyl-(1→2)-3,5-di-O-benzoyl-α-D-arabinofuranoside 
• 1448225-56-6 methyl 2,3-di-O-benzyl-5-O-(2-quinolinecarbonyl)-β-D-arabinofuranosyl-(1→2)-3,5-di-O-benzoyl-α-D-arabinofuranoside 
• 1448225-59-9 methyl 2,3-di-O-benzyl-5-O-(2-quinolinecarbonyl)-β-D-arabinofuranosyl-(1→2)-3,5-di-O-benzyl-α-D-arabinofuranoside 
• 1448225-61-3 methyl 2,3-di-O-benzyl-5-O-(2-quinolinecarbonyl)-β-D-arabinofuranosyl-(1→5)-2,3-di-O-benzoyl-α-D-arabinofuranoside 
• 1448225-62-4 methyl 2,3-di-O-benzyl-5-O-(2-quinolinecarbonyl)-β-D-arabinofuranosyl-(1→5)-2,3-di-O-benzyl-α-D-arabinofuranoside 
• 1448225-63-5 methyl 2,3-di-O-benzyl-5-O-(2-quinolinecarbonyl)-β-D-arabinofuranosyl-(1→3)-2-O-benzyl-4,6-O-benzylidene-α-D-glucopyranoside 
• 1448225-65-7 methyl 2,3-di-O-benzyl-5-O-(2-quinolinecarbonyl)-β-D-arabinofuranosyl-(1→6)-2,3,4-tri-O-benzoyl-α-D-glucopyranoside 
• 1448225-66-8 3-azidopropyl 2,3-di-O-benzyl-5-O-(2-quinolinecarbonyl)-β-D-arabinofuranosyl-(1→4)-2,3-di-O-benzoyl-6-O-acetyl-β-D-galactopyranoside 
• 1448225-69-1 3-azidopropyl 2,3-di-O-benzyl-5-O-(2-quinolinecarbonyl)-β-D-arabinofuranosyl-(1→6)-2,3,4-tri-O-benzoyl-α-D-galactopyranoside 
• 1448225-70-4 3-azidopropyl 2,3-di-O-benzyl-5-O-(2-quinolinecarbonyl)-β-D-arabinofuranosyl-(1→6)-2,3,4-tri-O-benzoyl-α-D-mannopyranoside 

Relevant academic research and scientific papers

Efficient synthesis of a linear octyl pentaarabinofuranoside, a substrate for mycobacterial EmbA/EmbB proteins

The efficient synthesis of a linear pentasaccharide with the structure 1, β-D-Araf-(1 → 2)-α-D-Araf-(1 → 5)-α-D-Araf-(1 → 5)-α-D-Araf-(1 → 5)-α-D-Araf-(1 → 5), as its octyl glycoside has been achieved through a convergent [3 + 2] coupling strategy. The difficult-to-obtain 1,2-cis-β-arabinofuranosidic bond at the non-reducing end of the target molecule was stereoselectively constructed by the use of a 2-quinolinecarbonyl-directed 1,2-cis glycosylation method.

β-arabinofuranosylation using 5- O -(2-quinolinecarbonyl) substituted ethyl thioglycoside donors

A new β-stereoselective d- and l-arabinofuranosylation method has been developed employing 5-O-(2-quinolinecarbonyl) substituted arabinosyl ethyl thioglycosides as glycosyl donors. The approach allows a wide range of acceptor substrates to be used; the β-selectivity is good-to-excellent. Stereoselective synthesis of a mannose-capped octasaccharide portion from a mycobacterial cell wall polysaccharide was then carried out to demonstrate the utility of this methodology.

Synthesis and TNF-α inducing activities of mycoloyl-arabinan motif of mycobacterial cell wall components

The extract of the cell wall skeleton of Bacillus Calmette-Guerin (BCG-CWS) from Mycobacterium bovis is known to be an activator of innate immunity. Synthesis of pentaarabinofuranoside as part of the arabinan moiety of BCG-CWS was achieved by double α-ara