886861-17-2

Basic information

• Product Name: 11β,16α,17α-trihydroxypregna-21-(2-methyl-1-oxopropoxy)-1,4-diene-3,20-dione
• Synonyms: 11β,16α,17α-trihydroxypregna-21-(2-methyl-1-oxopropoxy)-1,4-diene-3,20-dione
• CAS NO: 886861-17-2
• Molecular Weight: 446.541
• Mol File: 886861-17-2.mol
• Article Data: 0

Chemical Properties

• CAS DataBase Reference: 11β,16α,17α-trihydroxypregna-21-(2-methyl-1-oxopropoxy)-1,4-diene-3,20-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 11β,16α,17α-trihydroxypregna-21-(2-methyl-1-oxopropoxy)-1,4-diene-3,20-dione(886861-17-2)
• EPA Substance Registry System: 11β,16α,17α-trihydroxypregna-21-(2-methyl-1-oxopropoxy)-1,4-diene-3,20-dione(886861-17-2)

Safety Data

• Hazardous Substances Data: 886861-17-2(Hazardous Substances Data)

Usage

Chemical structure

A synthetic corticosteroid with a specific molecular structure that includes three hydroxyl groups at positions 11β, 16α, and 17α, a 21-(2-methyl-1-oxopropoxy) group, and a 1,4-diene-3,20-dione moiety.

Potency

Has potent anti-inflammatory and immunosuppressive properties.

Medical use

Commonly used in the treatment of a wide range of inflammatory and autoimmune conditions, including asthma, rheumatoid arthritis, and inflammatory bowel disease.

Mechanism of action

Binds to glucocorticoid receptors in the body and inhibits the production of inflammatory molecules, such as prostaglandins and leukotrienes.

Effects

Reduces inflammation, suppresses the immune response, and provides relief from pain, swelling, and other symptoms associated with inflammatory and autoimmune conditions.

Side effects

Can have a number of side effects, including increased susceptibility to infections and bone density loss.

Precautions

Must be used with caution and under the guidance of a healthcare professional.

Molecular weight

Approximately 430.53 g/mol

Appearance

Typically a white or off-white crystalline powder.

Solubility

Soluble in organic solvents, such as ethanol and methanol, and slightly soluble in water.

Stability

Stable under normal temperature and pressure conditions, but should be stored in a cool, dry place and protected from light to maintain its potency.

Dosage

The dosage of this corticosteroid depends on the specific condition being treated, the patient's individual needs, and the healthcare professional's recommendations.

Administration

Can be administered in various forms, such as oral tablets, injections, or inhalers, depending on the condition being treated and the patient's needs.

Downstream Products

• 126544-47-6 ciclesonide