88696-53-1Relevant academic research and scientific papers
Investigation of the Reactivities and Tautomerism of Azolidines. 42. 2-Iminothiazolidin-4-ones in the Mannich Reaction with Secondary Amines
Solov'eva, S. Yu.,Ramsh, S. M.,Ginak, A. I.
, p. 1076 - 1079 (2007/10/02)
The aminomethylation of 2-iminothiazolidin-4-one with aqueous formaldehyde and piperidine gives 2-piperidinomethylamino-5-hydroxymethyl-5-piperidinomethylthiazolin-4-one, as well as a compound with an unestablished structure, rather than 3-piperidinomethyl-2-iminothiazolidin-4-one, as was previously assumed.The aminomethylation of 2-iminothiazolidin-4-one with diphenylamine and diethylamine leads to the formation of 2-monoaminomethyl derivatives. 2-Imino-5-benzylidenethiazolidin-4-one reacts with paraformaldehyde and piperidine in benzene to give 2-piperidinomethylimino-3--5-benzylidenethiazolidin-4-one.
