88708-58-1

Basic information

• Product Name: Phosphonic acid, [2-hydroxy-3-phenyl-2-(phenylmethyl)propyl]-, dimethyl ester
• CAS NO: 88708-58-1
• Molecular Formula: C18H23O4P
• Molecular Weight: 334.352
• Mol File: 88708-58-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Phosphonic acid, [2-hydroxy-3-phenyl-2-(phenylmethyl)propyl]-, dimethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Phosphonic acid, [2-hydroxy-3-phenyl-2-(phenylmethyl)propyl]-, dimethyl ester(88708-58-1)
• EPA Substance Registry System: Phosphonic acid, [2-hydroxy-3-phenyl-2-(phenylmethyl)propyl]-, dimethyl ester(88708-58-1)

Safety Data

• Hazardous Substances Data: 88708-58-1(Hazardous Substances Data)

Upstream product

• 756-79-6 dimethyl methane phosphonate 
• 102-04-5 1,3-Diphenylpropanone 

Downstream Products

• 14213-80-0 2-benzyl-1-phenyl-2-propene 
• 7351-83-9 dimethyl phosphate anion 

Relevant articles and documents

The Olefin Synthesis from β-Hydroxyalkylphosphonates Induced by Fluorides or Relatively Weak Bases

β-Hydroxyalkylphosphonates, which were prepared readily from alkylphosphonates and carbonyl compounds, were treated with a fluoride ion such as CsF or with relatively weak bases such as K2CO3 in N,N-dimethylformamide to give the corresponding olefins in good yields. One molar equivalent of water to bases is effective for increasing the yields of olefins. The stereochemistry of erythro-dimethyl (2-hydroxy-1-methyl-2-phenyl)ethylphosphonate was determined by X-ray crystallographic analysis. Use of threo-isomer gave (E)-olefin exclusively, while that of erythro-enricned isomer afforded predominantly (Z)-olefin, indicating that the present olefination proceeds stereospecifically in a manner of syn-elimination.