88713-38-6Relevant articles and documents
Synthesis of acyclic analogs of C-nucleosides
Babin,Dinh,Igolen
, p. 1169 - 1179 (2007/10/02)
Direct nitrations of 2-carboxamido- and 2-cyano-Bz-methoxybenzofurans by nitric acid in acetic anhydride always yield two derivatives nitrated on the homocyclic ring at the ortho or, possibly, the para position to the methoxyl group. The proportions vary with the case in question. The methoxylated nitrocarboxamides and nitronitriles obtained can be demethylated by pyridinium chloride. Their hydrolysis into the corresponding acids is performed without demethylation by diluted sulfuric acid and, except in one case, with simultaneous demethylation by diluted soda.