887150-21-2Relevant articles and documents
Design and synthesis of novel photoaffinity reagents for labeling VEGF receptor tyrosine kinases
Han, Sun-Young,Choi, Seo Hyun,Kim, Myung Hee,Lee, Woo Ghil,Kim, Seong Hwan,Min, Yong Ki,Kim, Bum Tae
, p. 2915 - 2919 (2007/10/03)
Novel biotin-tagged photoaffinity probes based on a trifunctional tertiary amine scaffold were synthesized and evaluated as vascular endothelial growth factor receptor-2 (VEGFR-2) inhibitors. Probes 3a-c inhibit VEGF induced proliferation in HUVE cells, w