88718-92-7

Usage

Uses

Used in Pharmaceutical Industry:
2-Methyl-1H-imidazol-4-amine is used as a building block for the synthesis of pharmaceuticals. Its unique structure and reactivity contribute to the development of new drugs with potential therapeutic applications.
Used in Agrochemical Industry:
In the agrochemical industry, 2-Methyl-1H-imidazol-4-amine is utilized as a precursor in the production of agrochemicals. Its chemical properties allow for the creation of compounds that can be used in pest control and crop protection.
Used in Medicinal Chemistry:
2-Methyl-1H-imidazol-4-amine is employed as a key intermediate in medicinal chemistry. Its presence in various organic compounds enables the exploration of new chemical entities with potential therapeutic effects.
Used in Biochemistry:
In the field of biochemistry, 2-Methyl-1H-imidazol-4-amine serves as a component in the synthesis of bioactive molecules. Its incorporation into these molecules can lead to the discovery of new biochemical pathways and mechanisms.
Used in Material Science:
2-Methyl-1H-imidazol-4-amine is used as a building block in material science for the development of novel materials with specific properties. Its chemical structure and reactivity play a crucial role in the creation of advanced materials for various applications.

Upstream product

• 696-23-1 2-methyl-4-nitro-1H-imidazole 

Downstream Products

• 658057-77-3 5-(N,N-dimethylaminomethylidineamino)-2-methyl-1H-imidazole 

Relevant academic research and scientific papers

An aminoimidazole and its utility in heterocyclic synthesis

Aminoacetonitrile (1) reacted with acetamidinium chloride to give 4-aminoimidazole (4), which reacted with DMFDMA to yield imidazole derivative 7 and with benzylidinemalononitrile and ethoxymethylene malononitrile to give imidazo[1,5-a]pyrimidine derivatives 12 and 15. Compound 1 reacted with β-crotononitrile to yield pyridine derivative 20. Imidazo[1,2-a]pyridine derivative 23 could be obtained via the reaction of 20 with DMFDMA.

Synthesis and characterization of go-chit-ni nanocomposite as a recoverable nanocatalyst for reducing nitroarenes in water

In the present study, nickel nanoparticles (Ni-NPs) immobilized on graphene oxide-chitosan (GO-Chit-Ni) have been synthesized and characterized as a catalyst for reduction of nitroarenes in water. For this purpose, GO has been functionalized with chitosan (GO-Chit). Then, Ni-NPs were immobilized on the surface of GO-Chit using a simple method. The GO-Chi-Ni nanocomposites were characterized using Fourier Transforms Infrared Spectroscopy (FT-IR), Transmission Electron Microscopy (TEM), X-Ray Diffraction Measurements (XRD), and Atomic Adsorption Spectrometry (AAS). The GO-Chi-Ni nanoparticles demonstrated appropriate catalytic activity in reducing nitroarenes to aryl amines in the existence of sodium borohydride (NaBH4) aqueous solution as a hydrogen source at 80oC. This catalytic system applies environmentally benign water as a solvent that is cheap, easily accessible, non-toxic, non-volatile, non-flammable and thermally stable. This type of catalyst can be applied several times with no considerable change in its performance.

Magnetically Recoverable Gold Nanorods as a Novel Catalyst for the Facile Reduction of Nitroarenes Under Aqueous Conditions

Abstract: In this work, cysteine-functionalized Fe3O4@Carbon magnetic nanoparticles were used for the synthesis of gold nanorods. Fe3O4@C nanoparticles were first prepared by synthesis of Fe3O4magnetic nanoparticles (MNPs), and then carbon-coated MNPs (Fe3O4@C) were synthesized by glucose carbonization using a hydrothermal method. Finally, the gold NRs were loaded on the modified surface of Fe3O4@C MNPs. The designed magnetically recoverable gold nanorods, after full characterization by FTIR, SEM, TEM, TGA, VSM, XRD, and ICP-OES, were applied to the reduction of nitroarenes. The Fe3O4@C@Cys–Au nanorods showed higher performance than Fe3O4@C@Cys–Au nanospheres in a selective facile reduction of nitroarenes to the corresponding aminoarenes in aqueous medium at room temperature using NaBH4. Graphical Abstract: [Figure not available: see fulltext.]

Novel imidazole compounds and use of these compounds for dyeing keratinous fibers

The disclosure relates to novel imidazole compounds which can be useful as couplers for the oxidation dyeing of keratinous fibers. The present disclosure also relates to a dyeing composition for dyeing keratinous fibers comprising at least one oxidation base and at least one coupler of the imidazole type as disclosed herein, and the dyeing method using this composition.

Efficient reduction of nitroarenes in water catalyzed by reusable Pd nanoparticles immobilized on chitosan-functionalized graphene oxide

Graphene oxide was functionalized with chitosan for palladium immobilization (GO-Chit-Pd), which was used as an efficient catalyst for the reduction of aromatic nitro compounds using sodium borohydride in water. To achieve the best catalytic efficacy, various parameters such as temperature, solvent, mole ratio of hydrogen sources, and the amount of catalyst were optimized. The method has been applied to the reduction of a broad range of nitroarenes with different properties. The easy purification, convenient operation, environmental friendliness, and high product yields render this method viable for use. The nanocatalyst can be easily separated and efficiently recovered and reused for multiple cycles without appreciable loss in its catalytic activity.