88718-92-7

Basic information

• Product Name: 2-METHYL-1H-IMIDAZOL-4-AMINE
• Synonyms: 2-METHYL-1H-IMIDAZOL-4-AMINE;1H-IMidazol-5-aMine, 2-Methyl-;2-methyl-1H-imidazol-5-amine
• CAS NO: 88718-92-7
• Molecular Formula: C₄H₇N₃
• Molecular Weight: 97.12
• Mol File: 88718-92-7.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 400.8 °C at 760 mmHg
• Flash Point: 225 °C
• Appearance: /
• Density: 1.221 g/cm³
• Storage Temp.: 2-8°C(protect from light)
• CAS DataBase Reference: 2-METHYL-1H-IMIDAZOL-4-AMINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-METHYL-1H-IMIDAZOL-4-AMINE(88718-92-7)
• EPA Substance Registry System: 2-METHYL-1H-IMIDAZOL-4-AMINE(88718-92-7)

Safety Data

• Hazardous Substances Data: 88718-92-7(Hazardous Substances Data)

Usage

General Description

2-Methyl-1H-imidazol-4-amine is a chemical compound with the molecular formula C4H7N3. This organic compound belongs to the class of imidazole derivatives and contains an imidazole ring with a methyl group and an amino group attached to it. It is commonly used as a building block in the synthesis of pharmaceuticals, agrochemicals, and other organic compounds. 2-Methyl-1H-imidazol-4-amine has potential applications in fields such as medicinal chemistry, biochemistry, and material science. Its chemical properties and reactivity make it a valuable intermediate in the production of various functionalized compounds.

Upstream product

• 696-23-1 2-methyl-4-nitro-1H-imidazole 

Downstream Products

• 658057-77-3 5-(N,N-dimethylaminomethylidineamino)-2-methyl-1H-imidazole 

Relevant articles and documents

An aminoimidazole and its utility in heterocyclic synthesis

Aminoacetonitrile (1) reacted with acetamidinium chloride to give 4-aminoimidazole (4), which reacted with DMFDMA to yield imidazole derivative 7 and with benzylidinemalononitrile and ethoxymethylene malononitrile to give imidazo[1,5-a]pyrimidine derivatives 12 and 15. Compound 1 reacted with β-crotononitrile to yield pyridine derivative 20. Imidazo[1,2-a]pyridine derivative 23 could be obtained via the reaction of 20 with DMFDMA.

Magnetically Recoverable Gold Nanorods as a Novel Catalyst for the Facile Reduction of Nitroarenes Under Aqueous Conditions

Abstract: In this work, cysteine-functionalized Fe3O4@Carbon magnetic nanoparticles were used for the synthesis of gold nanorods. Fe3O4@C nanoparticles were first prepared by synthesis of Fe3O4magnetic nanoparticles (MNPs), and then carbon-coated MNPs (Fe3O4@C) were synthesized by glucose carbonization using a hydrothermal method. Finally, the gold NRs were loaded on the modified surface of Fe3O4@C MNPs. The designed magnetically recoverable gold nanorods, after full characterization by FTIR, SEM, TEM, TGA, VSM, XRD, and ICP-OES, were applied to the reduction of nitroarenes. The Fe3O4@C@Cys–Au nanorods showed higher performance than Fe3O4@C@Cys–Au nanospheres in a selective facile reduction of nitroarenes to the corresponding aminoarenes in aqueous medium at room temperature using NaBH4. Graphical Abstract: [Figure not available: see fulltext.]

Efficient reduction of nitroarenes in water catalyzed by reusable Pd nanoparticles immobilized on chitosan-functionalized graphene oxide

Graphene oxide was functionalized with chitosan for palladium immobilization (GO-Chit-Pd), which was used as an efficient catalyst for the reduction of aromatic nitro compounds using sodium borohydride in water. To achieve the best catalytic efficacy, various parameters such as temperature, solvent, mole ratio of hydrogen sources, and the amount of catalyst were optimized. The method has been applied to the reduction of a broad range of nitroarenes with different properties. The easy purification, convenient operation, environmental friendliness, and high product yields render this method viable for use. The nanocatalyst can be easily separated and efficiently recovered and reused for multiple cycles without appreciable loss in its catalytic activity.