887239-61-4Relevant academic research and scientific papers
Palladium-catalyzed cascade one-pot synthesis of 5-arylmethylisoxazolidines from N-homoallylhydroxylamines with aryl bromides
Jiang, Dahong,Peng, Jinsong,Chen, Yuanwei
, p. 1641 - 1647 (2008/09/18)
A novel method for the synthesis of 5-arylmethylisoxazolidines via palladium-catalyzed reactions of aryl bromides with N-homoallylhydroxylamines is described. This reaction effects intramolecular C-O bond formation with concomitant intermolecular formatio
Stereoselective synthesis of isoxazolidines through Pd-catalyzed carboetherification of N-butenylhydroxylamines
Hay, Michael B.,Wolfe, John P.
, p. 6492 - 6494 (2008/09/16)
(Chemical Equation Presented) Pd ploy to isoxazolidines: Carboetherification reactions of N-butenylhydroxylamines with aryl bromides afford substituted isoxazolidines in good yield with up to > 20:1 d.r. These transformations provide a new strategy for th
The 5-endo-trig cyclization of D-glucose derived γ-alkenylamines with mercury (II) salts: Synthesis of 1-deoxy-castanospermine and its 8a-epi-analogue
Dhavale, Dilip D.,Jachak, Santosh M.
, p. 893 - 900 (2007/10/03)
The intramolecular aminomercuration of γ-alkenylamines 1a, 1b and 4 was shown to afford the 5-endo-trig cyclized product exclusively in good yield. The utility of pyrrolidine derivatives thus obtained from D-glucose derived γ-alkenylamines 1a and 1b was d
A New Route to 3,5-Disubstituted Isoxazolidines via the Iodocyclization of Homoallylic Hydroxylamines
Mancini, Fabrizio,Piazza, Maria Giulia,Trombini, Claudio
, p. 4246 - 4252 (2007/10/02)
N,N-Dialkyl-O-trialkylsilyl homoallylic hydroxylamines reacted with iodine, N-iodosuccinimide, or iodine chloride to give 3,5-disubstituted isoxazolidines in good yield.The relative configuration that was generated at C3 and C5 was controlled by the natur
