887274-98-8

Upstream product

• 221201-21-4 (R)-5-(azidomethyl)-3-(3-fluoro-4-(piperazin-1-yl)phenyl)oxazolidin-2-one 
• 154590-63-3 [N-3-(1-tert-butoxycarbonyl)-4-(2-fluoro-4-piperazinyl)-2-oxo-5-oxazolidinyl]methyl methanesulfonate 
• 154590-64-4 (S)-N-[3-[3-fluoro-4-[N-t-butoxycarbonylpiperazin-1-yl]phenyl]-2-oxooxazolidin-5-ylmethyl]azide 
• 154590-62-2 (R)-tert-butyl-4-(2-fluoro-4-(5-(hydroxymethyl)-2-oxooxazolidin-3-yl)phenyl)piperazine-1-carboxylate 

Downstream Products

• 887275-15-2 (S)-N-[[3-[3-fluoro-4-[4-(cyanomethyl)-1-piperazinyl]phenyl]-2-oxo-5-oxazolidinyl]-methyl]-O-methylthiocarbamate 
• 887275-04-9 {(S)-3-[4-(4-Cyanomethyl-piperazin-1-yl)-3-fluoro-phenyl]-2-oxo-oxazolidin-5-ylmethyl}-carbamic acid methyl ester 
• 154590-61-1 N-{3-[4-(4-cyanomethyl-piperazin-1-yl)-3-fluoro-phenyl]-2-oxo-oxazolidin-5-ylmethyl}-acetamide 
• 887275-12-9 (S)-N-[[3-[3-fluoro-4-[4-(cyanomethyl)-1-piperazinyl]phenyl]-2-oxo-5-oxazolidinyl]methyl]thioacetamide 
• 887275-08-3 N-{3-[4-(4-cyanomethyl-piperazin-1-yl)-3-fluoro-phenyl]-2-oxo-oxazolidin-5-ylmethyl}-2,2-difluoro-acetamide 

Relevant academic research and scientific papers

Synthesis and antibacterial activity of novel oxazolidinones bearing N-hydroxyacetamidine substituent

Novel oxazolidinone antibacterials containing N-hydroxyacetamidine moiety are synthesized with the diversity at C-5 terminus. These compounds have been evaluated against a panel of clinically relevant Gram-positive and Gram-negative pathogens. Most of the

Oxazolidinone antibacterial agents having a thiocarbonyl functionality

The present invention provides compounds of Formula 1: or pharmaceutical acceptable salts thereof wherein A, G and R1are as defined in the claims which are antibacterial agents.