887279-00-7

Basic information

• Product Name: 2-[8-(3-{[(4-fluoro-benzyl)-(4-methylsulfanyl-phenyl)-amino]-methyl}-phenyl)-quinolin-6-yl]-2-methyl-propionitrile
• CAS NO: 887279-00-7
• Molecular Weight: 531.697
• Mol File: 887279-00-7.mol

Chemical Properties

• CAS DataBase Reference: 2-[8-(3-{[(4-fluoro-benzyl)-(4-methylsulfanyl-phenyl)-amino]-methyl}-phenyl)-quinolin-6-yl]-2-methyl-propionitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 2-[8-(3-{[(4-fluoro-benzyl)-(4-methylsulfanyl-phenyl)-amino]-methyl}-phenyl)-quinolin-6-yl]-2-methyl-propionitrile(887279-00-7)
• EPA Substance Registry System: 2-[8-(3-{[(4-fluoro-benzyl)-(4-methylsulfanyl-phenyl)-amino]-methyl}-phenyl)-quinolin-6-yl]-2-methyl-propionitrile(887279-00-7)

Safety Data

• Hazardous Substances Data: 887279-00-7(Hazardous Substances Data)

Upstream product

• 87199-16-4 3-Formylphenylboronic acid 
• 346630-02-2 2-[8-(3-formyl-phenyl)-quinolin-6-yl]-2-methyl-propionitrile 
• 346630-01-1 2-(8-bromo-quinolin-6-yl)-2-methyl-propionitrile 
• 887278-98-0 2-methyl-2-(8-{3-[(4-methylsulfanyl-phenylamino)-methyl]-phenyl}-quinolin-6-yl)-propionitrile 
• 459-46-1 4-Fluorobenzyl bromide 

Relevant articles and documents

Nitrogen-bridged substituted 8-arylquinolines as potent PDE IV inhibitors

Potent inhibitors of the human PDE IV enzyme are described. Substituted 8-arylquinoline analogs bearing nitrogen-linked side chain were identified as potent inhibitors based on the SAR described herein. The pharmacokinetic profile of the best analog and t