88729-23-1Relevant articles and documents
Studies on anabolic steroids. 9. Tertiary sulfates of anabolic 17α-methyl steroids: synthesis and rearrangement
Bi, Honggang,Masse, Robert,Just, George
, p. 306 - 312 (2007/10/02)
A simple and convenient method has been developed to prepare sulfates of anabolic 17β-hydroxy-17α-methyl steroids.The sulfates of methandienone, 17α-methyltestosterone, mestanolone, oxandrolone, and stanozolol were prepared.Different A-ring functions were not affected under the sulfation condition.The buffered hydrolyses of these sulfates provided the 17-epimers of the original steroids and 17,17-dimethyl-18-nor-13(14)-ene steroids, presumably via the 17-carbocations. Keywords: steroids, tertiary sulfates; 17α-methyl steroids; 17β-methyl steroids; 17,17-dimethyl-18-norandrost-13(14)-enes; NMR
Proton magnetic resonance spectra of 17ξ-hydroxy-17ξ-methyl-5ξ-androstane C-3 ketone and C-3ξ alcohol isomers in chloroform-d and pyridine-d5
Templeton,Choi Jackson
, p. 485 - 491 (2007/10/02)
17α-Hydroxy-17β-methyl-5β-androstan-3-one,17β-methyl-5α-androstane-3α ,17α-diol,17β-methyl-5α-androstane-3β,17α-diol, 17α-methyl-5β-androstane-3β,17β-diol,17β-methyl-5β-androstane- 3α,17α-diol and 17β-methyl-5β-androstane-3β,17α-diol were synthesized for the first time. 1H NMR spectra of all four 17ξ-hydroxy/17ξ-methyl C-3 ketones and all eight C-3 alcohols were recorded in chloroform-d and pyridine-d5. Pyridine-induced chemical shifts are discussed. Thin-layer chromatographic data are given.