887324-52-9

Basic information

• Product Name: Atorvastatin
• Synonyms: Atorvastatin
• CAS NO: 887324-52-9
• Molecular Weight: 558.65
• Mol File: 887324-52-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Atorvastatin(CAS DataBase Reference)
• NIST Chemistry Reference: Atorvastatin(887324-52-9)
• EPA Substance Registry System: Atorvastatin(887324-52-9)

Safety Data

• Hazardous Substances Data: 887324-52-9(Hazardous Substances Data)

Upstream product

• 134394-96-0 *,S^*)>-5-<2-(4-fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-<(phenylamino)carbonyl>-1H-pyrrol-1-yl>-3-hydroxy-1-pentanoic acid, 2-hydroxy-1,2,2-triphenylethyl ester 

Downstream Products

• 134394-98-2 1,1-dimethylethyl (R)-7-<2-(4-fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-<(phenylamino)carbonyl>-1H-pyrrol-1-yl>-5-hydroxy-3-oxo-1-heptanoate 

Relevant articles and documents

Synthesis of some impurities and/or degradation products of atorvastatin

Synthesis of some impurities and/or degradation products of atorvastatin, calcium (3R,5R)-7-[2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl) pyrrol-1-yl]-3,5-dihydroxyheptanoate, is described. These include its desfluoro analog, the corresponding (3S,5S)-and (3S,5R)-epimers, atorvastatin lactone, and some other potential impurities. The synthesized compounds as well as the corresponding intermediates were characterized by 1H NMR, 13C NMR and MS.