887344-26-5Relevant academic research and scientific papers
SnAP reagents for the transformation of aldehydes into substituted thiomorpholines - An alternative to cross-coupling with saturated heterocycles
Vo, Cam-Van T.,Mikutis, Gediminas,Bode, Jeffrey W.
supporting information, p. 1705 - 1708 (2013/04/10)
It's a SnAP! The transformation of aldehydes into N-unsubstituted 3-thiomorpholines provides a convenient alternative to metal-catalyzed cross-coupling reactions, which are generally unsuited to the functionalization of saturated N-heterocycles. A copper-mediated radical cyclization is the key to the mild conditions, high functional group tolerance, and broad substrate scope offered by these reagents. Copyright
