887375-50-0Relevant academic research and scientific papers
Chiral Pd-catalyzed trifluoropyruvate-ene reactions with steroidal side chains for late-stage fluoromethyl-functionalization: remarkably high agonist activities of ene products even in low VDR binding affinity
Fujita, Kumiko,Aida, Junpei,Mikami, Koichi
, p. 6402 - 6408 (2015)
Abstract The highly enantioselective trifluoropyruvate-ene reactions of chiral steroid side chain olefins were achieved by dicationic palladium complexes as chiral Lewis acid catalysts to give steroidal ene-products in high diastereoselectivity. The ene p
METHOD FOR PRODUCING OPTICALLY ACTIVE FLUORINE-CONTAINING CARBONYL-ENE PRODUCT
-
Page/Page column 20-21; 29-30, (2009/09/26)
An optically active, fluorine-containing carbonyl-ene product is produced by reacting a fluorine-containing α-ketoester with an alkene in the presence of a transition metal complex having an optically active ligand. There are Mode 1 of conducting this rea
