88738-08-3Relevant academic research and scientific papers
Bifunctional polymeric organocatalysts and their application in the cooperative catalysis of Morita-Baylis-Hillman reactions
Kwong, Cathy Kar-Wing,Huang, Rui,Zhang, Minjuan,Shi, Min,Toy, Patrick H.
, p. 2369 - 2376 (2008/02/02)
A series of soluble, noncross-linked polystyrene-supported tri-phenylphosphane and 4-dimethylaminopyridine reagents were prepared. Some of these polymeric reagents contained either alkyl alcohol or phenol groups on the polymer backbone. The use of these materials as organocatalysts in a range of Morita-Baylis-Hillman reactions indicated that hydroxyl groups could participate in the reactions and accelerate product formation. In the cases examined, phenol groups were more effective than alkyl alcohol groups for catalyzing the reactions. This article is one of the first reports of the synthesis and use of non-natural, bifunctional polymeric reagents for use in organic synthesis in which both functional groups can cooperatively participate in the catalysis of reactions.
Influence of Michael acceptor stereochemistry on intramolecular Morita-Baylis-Hillman reactions
Teng, Wen-Dong,Huang, Rui,Kwong, Cathy Kar-Wing,Shi, Min,Toy, Patrick H.
, p. 368 - 371 (2007/10/03)
A study of the effect of Michael acceptor stereochemistry on the efficiency of intramolecular Morita-Baylis-Hillman (MBH) reactions has been performed. The reactions were catalyzed by a phosphine, and the reaction substrates studied were enones containing
SOME UNUSUAL REACTIONS OF MOLECULAR OXYGEN WITH BICYCLIC DIAZENES WHICH TYPICALLY SERVE AS PRECURSORS TO ALKYLIDENECYCLOPENTANE-1,3-DIYLS; PEROXIDE FORMATION
Little, R. Daniel,Losinski-Dang, Lorraine,Venegas, Manuel G.,Merlic, Craig
, p. 4499 - 4502 (2007/10/02)
The reaction of a series of substituted bicyclic diazenes with oxygen was investigated.Three types of products result, namely ketoalcohols 2b-f, ketoaldehydes 4e-g and dioxolanes 3e-g.The potential intermediacy of an endoperoxide 5f is considered.
