88738-87-8

Upstream product

• 88738-86-7 methyl (E)-3-[4-(bromomethyl)phenyl]prop-2-enoate 
• 603-35-0 triphenylphosphine 
• 20754-20-5 3-p-tolyl-acrylic acid methyl ester 
• 1866-39-3 trans-p-methylcinnamic acid 

Downstream Products

• 88738-88-9 (E)-3-[((E)-4-Propenyl)-phenyl]-acrylic acid methyl ester 
• 88738-89-0 (E)-3-[((E)-4-Propenyl)-phenyl]-prop-2-en-1-ol 
• 88738-90-3 1-((E)-3-Bromo-propenyl)-4-((E)-propenyl)-benzene 
• 88738-91-4 Trimethyl-{(E)-3-[((E)-4-propenyl)-phenyl]-allyl}-ammonium; hydroxide 

Relevant academic research and scientific papers

A 1,10-HOFMANN ELIMINATION. SYNTHESIS OF A PARACYCLOPHANE TETRAENE

The synthesis of (E,E,E,E)-paracyclophane-1,5,13,17-tetraene via the cyclodimerization of 7,8-divinyl-p-quinodimethane is described.

One-pot synthesis of gem-difluorostyrenes from benzyl bromide via olefination of phosphonium ylide with difluorocarbene

A new approach for the synthesis of gem-difluorostyrenes from benzyl bromide is described. Quaternization of triphenylphosphine with benzyl bromide to give phosphonium salts, deprotonation of the corresponding phosphonium salts to produce phosphonium ylide, and the subsequent olefination of phosphonium ylide with difluorocarbene generated from difluoromethylene phosphobetaine (Ph3P+CF2CO2-) by decarboxylation can occur smoothly in one-pot, furnishing the final gem-difluorostyrenes in good yields.