88745-29-3 Usage
Description
(2E)-2-[(dimethylamino)methylidene]cyclohexylidenepropanedinitrile is a dinitrile compound with the molecular formula C13H18N2, featuring a cyclohexylidene and dimethylamino functional groups. It is a compound of interest in various scientific fields due to its unique structure and properties.
Uses
Used in Organic Chemistry Research:
(2E)-2-[(dimethylamino)methylidene]cyclohexylidenepropanedinitrile is used as a research compound in the field of organic chemistry for studying its properties and potential applications.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, (2E)-2-[(dimethylamino)methylidene]cyclohexylidenepropanedinitrile is used as a starting material or intermediate for the synthesis of various pharmaceutical compounds, leveraging its unique structure to develop new drugs.
Used in Materials Science:
(2E)-2-[(dimethylamino)methylidene]cyclohexylidenepropanedinitrile is also utilized in materials science as a component in the development of novel materials with specific properties, such as improved strength, flexibility, or chemical resistance.
It is important to handle (2E)-2-[(dimethylamino)methylidene]cyclohexylidenepropanedinitrile with care, as it may possess hazardous properties, and appropriate precautions should be taken during its handling and use.
Check Digit Verification of cas no
The CAS Registry Mumber 88745-29-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,8,7,4 and 5 respectively; the second part has 2 digits, 2 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 88745-29:
(7*8)+(6*8)+(5*7)+(4*4)+(3*5)+(2*2)+(1*9)=183
183 % 10 = 3
So 88745-29-3 is a valid CAS Registry Number.
88745-29-3Relevant articles and documents
Improved synthesis of mono- and disubstituted 2-halonicotinonitriles from alkylidene malononitriles
Longstreet, Ashley R.,Campbell, Brian S.,Gupton, B. Frank,McQuade, D. Tyler
supporting information, p. 5298 - 5301 (2013/11/06)
Pyridines with 2,3,4 and/or 5 substitution remain challenging to prepare. Existing strategies to form multisubstituted 2-halonicotinonitriles via enamines suffer from dimerization of the starting alkylidene malononitriles resulting in low yields. Through alteration of reaction conditions, a new high yielding method into enamines was realized by condensing DMF-DMA and alkylidene malononitriles in the presence of substoichiometric acetic anhydride. Cyclization of the resulting enamines under Pinner conditions provided 2-halonicotinonitriles in high overall yields.
ACETALS OF LACTAMS AND ACID AMIDES. 39. SYNTHESIS OF THREE-RING DERIVATIVES OF PYRIDOPYRIMIDINES ON THE BASIS OF THE REACTION OF DIMETHYLFORMAMIDE ACETAL WITH DICYANOMETHYLENECYCLOALKANES
Granik, V. G.,Smetskaya, N. I.,Mukhina, N. A.,Persianova, I. V.,Klimenko, V. G.
, p. 1027 - 1030 (2007/10/02)
The reaction of dicyanomethylenecyclopentane and -cyclohexane with dimethylformamide diethylacetal was used to synthesize dieneamino nitriles, from which isoquinoline and 2-pyridine derivatives were obtained by treatment with ammonia.The reaction of 3-ami
