88746-58-1Relevant academic research and scientific papers
Carbocyclic derivatives
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, (2008/06/13)
The present invention relates to compounds of formula (I) or a monomethyl or monoethyl ether thereof (the compound of formula (I) including these ethers may contain no more than 30 carbon atoms in total); ethers, esters, thereof; acid addition salts there
2-[(arylmethyl)amino]-2-methyl-1,3-propanediol DNA intercalators. An examination of the effects of aromatic ring variation on antitumor activity and DNA binding
Bair,Andrews,Tuttle,Knick,Cory,McKee
, p. 1983 - 1990 (2007/10/02)
The effects of variation of aromatic ring size, shape, and side-chain position on antitumor activity and DNA binding in a series of carbocyclic 2-[(arylmethyl)amino]-2-methyl-1,3-propanediols (AMAPs) were examined. In general, the interaction of AMAPs wit
Synthesis and Mutagenicity of Dihydrodiol Metabolites of Benzofluoranthene
Amin, Shantu,Hussain, Nalband,Brielmann, Harry,Hecht, Stephen S.
, p. 1091 - 1095 (2007/10/02)
The syntheses of the two major hepatic microsomal dihydrodiol metabolites of the environmental carcinogen, benzofluoranthene, are described. 1,2-Dihydro-1,2-dihydroxybenzofluoranthene was prepared from 11H-benzofluorene-11-carboxylic acid.The key
