88754-05-6

Upstream product

• 88754-03-4 trans-4-phenyl-1-(1-propynyl)cyclohexyl acetate 
• 75583-57-2 lithium bis(dimethyl(phenyl)silyl)cuprate 
• 88754-04-5 cis-4-phenyl-1-(1-propynyl)cyclohexyl acetate 
• 3839-31-4 dimethyl(phenyl)silyllithium 
• 115884-55-4 trans-4-phenyl-1-prop-1-ynylcyclohexyl N-phenylcarbamate 
• 91621-56-6 trans-4-phenyl-1-prop-1-ynylcyclohexanol 

Downstream Products

• 88754-20-5 (4-Prop-1-ynyl-cyclohexyl)-benzene 
• 88754-21-6 (4-Prop-1-ynyl-cyclohexyl)-benzene 

Relevant academic research and scientific papers

STEREOSPECIFICITY IN THE SYNTHESIS OF ALLYLSILANES FROM TERTIARY ALLYLIC ACETATES

The tertiary allylic acetates (1-4) and the propargylic acetates (14 and 15) react with our silyl-cuprate reagent (5) to give, in a cleanly anti manner, the stereodefined allylsilanes (6 and 7) and allenylsilanes (16 and 17).

Synthesis of Allenylsilanes from Propargyl Carbamates

Pent-3-yn-2-yl acetate (1) reacts with dimethyl(phenyl)silyl cuprate reagent to give a mixture of allenylsilane and propargylsilane.The corresponding N-phenylcarbamate (4) gives only the allenylsilane.Four other examples of this regioselective reaction are reported.The stereochemistry is largely syn.