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Usage

Uses

Used in Pharmaceutical Industry:
(+/-)-1β-amino-2α,3α-O-isopropylidene-2α,3α,4β-cyclopentanetriol is used as a building block or intermediate in the synthesis of various pharmaceutical compounds. Its unique structure and functional groups make it a versatile molecule for the development of new drugs with potential therapeutic applications.
Used in Chemical Synthesis:
(+/)-1β-amino-2α,3α-O-isopropylidene-2α,3α,4β-cyclopentanetriol can be used as a starting material or intermediate in the synthesis of various organic compounds, including natural products, pharmaceuticals, and other bioactive molecules. Its unique structure and functional groups allow for further chemical modifications and the development of new compounds with potential applications in various fields.
Used in Research and Development:
(+/-)-1β-amino-2α,3α-O-isopropylidene-2α,3α,4β-cyclopentanetriol can be used as a research tool in various scientific studies, including the investigation of its chemical properties, reactivity, and potential applications in different fields. It can also be used as a reference compound for the development of new analytical methods and techniques for the analysis and characterization of similar compounds.

Upstream product

• 542-92-7 cyclopenta-1,3-diene 
• 59438-64-1 (+/-)-3-(3,5-dinitrobenzoyl)-2-oxa-3-azabicyclo<2.2.1>hept-5-ene 
• 99027-88-0 N-(benzyloxycarbonyl)-2-oxa-3-azabicyclo<2.2.1>hept-5-ene 

Downstream Products

• 135700-57-1 (+/-)-(1α,2β,3β,4α)-4-<<2-amino-6-chloro-5-<(4-chlorophenyl)azo>pyrimidin-2-yl>amino>-2,3-O-isopropylidene-1,2,3-cyclopentanetriol 
• 142635-42-5 (+/-)-5'-Noraristeromycin 
• 1154413-15-6 (3aS,4R,6S,6aR)-6-hydroxy-2,2-dimethyltetrahydro-3aH-cyclo-penta[d][1,3]dioxol-4-aminium (2R,3R)-2,3-bis(benzoyloxy)-3-carboxypropanoate dibenzoyl-L-tartrate 
• 376608-75-2 2-({(3aR,4S,6R,6aS)-6-[7-chloro-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidine-3-yl]-2,2-dimethyltetrahydro-3aH-cyclopentadiene[d][1,3]dioxolene-4-yl}oxy)ethanol 
• 376608-74-1 2-[((3aR,4S,6R,6aS)-6-[[5-amino-6-chloro-2-(propylsulfanyl)-4-pyrimidinyl]amino]-2,2-dimethyltetrahydro-3aH-cyclopenta[d][1,3]dioxol-4-yl)oxy]-1-ethanol 
• 274693-55-9 [3aR-(3aα,4α,6α,6aα)]-2-[[6-amino-2,2-dimethyl tetrahydro-4H-cyclopenta-1,3-dioxol-4-yl]oxy]ethanol 
• 274693-54-8 benzyl 6-(2-hydroxyethoxy)-2,2-dimethyltetrahydro-3aH-cyclopenta[d][1,3]dioxol-4-ylcarbamate 
• 274693-53-7 [3aS-(3aα,4α,6α,6aα)]-(tetrahydro-6-hydroxy-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-yl)carbamic acid phenylmethyl ester 
• 274693-26-4 [3aR-[3aα,4α,6α,(1R,2S),6aα]]-2-[6-[[[7-(2-(3,4-difluorophenyl)cyclopropyl)]amino-5-(propylthio)-3H-1,2,3-triazolo[4,5-d]pyrimidin-3-yl]tetrahydro-2,2-dimethyl-4H-cyclopenteno-1,3-dioxolan-4-yl]oxy]ethanol 
• 1392909-34-0 (3aR,4S,6R,6aS)-6-amino-2,2-dimethyltetrahydro-3aH-cyclopenta-[d][1,3]dioxol-4-ol R-(-)-3-chloromandelate 
• 1392909-30-6 (3aR,4S,6R,6aS)-6-amino-2,2-dimethyltetrahydro-3aH-cyclopenta-[d][1,3]dioxol-4-ol D-(-)-mandelate 

Relevant academic research and scientific papers

A PROCESS FOR THE PREPARATION OF (3AR,4S, 6R, 6AS)-6-AMINO-2, 2- DIMETHYLTETRAHYDRO-3AH-CYCLOPENTA[D] [1,3] DIOXOL-4-OL DIBENZOYL-L-TARTRATE AND TO PRODUCTS OF SAID PROCESS

The present invention is directed to a process for the preparation of a diastereomerically pure dibenzoyl-L-tartrate salt of a compound of formula (III) and to products of said process.

2-Aza-3-Oxabicyclo[2.2.1]heptene hydrochloride: An exceptionally versatile synthon for carbocyclic sugars and nucleosides

The transformation of cyclopentadiene to 5'-desmethylene 1'-aza carbocyclic sugars has been achieved in four steps: 1. Cycloaddition of chloronitrosocyclohexane to 2-aza-3-oxabicyclo[2.2.1]heptene hydrochloride in EtOH-Et2O, 2. Nitrogen functionalization, 3. cis hydroxylation and 4. N-O bond cleavage. The protocols provided enable practical access to a range of 5'-desmethylene carbocyclic sugar analogs whose utility has been illustrated with synthesis of a novel 5'-desmethylene analog of aristeromycin.