887582-84-5

Basic information

• Product Name: 3-(2-chloroethyl)-4H-pyrido[1,2-a]pyrimidin-4-one
• Synonyms: 3-(2-chloroethyl)-4H-pyrido[1,2-a]pyrimidin-4-one
• CAS NO: 887582-84-5
• Molecular Formula: C10H9ClN2O
• Molecular Weight: 208.64
• Mol File: 887582-84-5.mol
• Article Data: 0

Chemical Properties

• Melting Point: 109-111 ºC
• Boiling Point: 341.5 °C at 760 mmHg
• Flash Point: 160.3 °C
• Appearance: /
• Density: 1.31
• Vapor Pressure: 8E-05mmHg at 25°C
• Refractive Index: 1.623
• CAS DataBase Reference: 3-(2-chloroethyl)-4H-pyrido[1,2-a]pyrimidin-4-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(2-chloroethyl)-4H-pyrido[1,2-a]pyrimidin-4-one(887582-84-5)
• EPA Substance Registry System: 3-(2-chloroethyl)-4H-pyrido[1,2-a]pyrimidin-4-one(887582-84-5)

Safety Data

• Hazardous Substances Data: 887582-84-5(Hazardous Substances Data)

Usage

General Description

3-(2-chloroethyl)-4H-pyrido[1,2-a]pyrimidin-4-one, also known as Temozolomide, is a chemotherapy drug used to treat certain types of brain tumors, particularly glioblastoma multiforme. It works by damaging the DNA in cancer cells, which leads to their destruction. Temozolomide is an oral medication that is often used in combination with radiation therapy to improve outcomes for patients with brain tumors. Common side effects of Temozolomide include nausea, vomiting, and low blood cell counts, and it should only be used under the supervision of a qualified healthcare professional.

InChI:InChI=1/C10H9ClN2O/c11-5-4-8-7-12-9-3-1-2-6-13(9)10(8)14/h1-3,6-7H,4-5H2