887586-33-6 Usage
Chemical structure
1-CYCLOHEXYL-3-(TERT-BUTYLDIMETHYLSILYL)-2-PROPYN-1-OL is a complex organic molecule consisting of a cyclohexyl group, a tert-butyldimethylsilyl group, and a propynyl group attached to an alcohol functional group.
Building block
It is commonly used as a building block in organic synthesis, particularly in the formation of complex organic molecules.
Protection
The tert-butyldimethylsilyl group provides protection for other functional groups during chemical reactions.
Reactivity
The propynyl group can react with other compounds to form new chemical bonds.
Stability
The cyclohexyl group provides stability and rigidity to the molecule.
Applications
This chemical is often used in the pharmaceutical and agrochemical industries for the production of various drugs and agricultural chemicals.
Check Digit Verification of cas no
The CAS Registry Mumber 887586-33-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,8,7,5,8 and 6 respectively; the second part has 2 digits, 3 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 887586-33:
(8*8)+(7*8)+(6*7)+(5*5)+(4*8)+(3*6)+(2*3)+(1*3)=246
246 % 10 = 6
So 887586-33-6 is a valid CAS Registry Number.
887586-33-6Relevant articles and documents
Asymmetric hydrogenation of alkynyl ketones with the η6- arene/TsDPEN-ruthenium(II) catalyst
Arai, Noriyoshi,Satoh, Hironori,Utsumi, Noriyuki,Murata, Kunihiko,Tsutsumi, Kunihiko,Ohkuma, Takeshi
supporting information, p. 3030 - 3033 (2013/07/26)
Enantioselective hydrogenation of alkynyl ketones catalyzed by Ru(OTf)(TsDPEN)(η6-p-cymene) (TsDPEN = N-(p-toluenesulfonyl)-1,2- diphenylethylenediamine) affords the propargylic alcohols in up to 97% ee. The alkynyl moieties are left intact in most cases. The reaction can be conducted with a substrate-to-catalyst molar ratio as high as 5000 under 10 atm of H 2. The mode of enantioselection is elucidated with the transition state models directed by the CH/π attractive interaction between the substrate and the catalytic species.
