887587-50-0 Usage
General Description
6-Bromo-4-chloro-quinoline-2-carboxylic acid methyl ester is a chemical compound with the molecular formula C11H7BrClNO2. It is a methyl ester derivative of 6-bromo-4-chloro-quinoline-2-carboxylic acid and is commonly used as an intermediate in the synthesis of pharmaceutical compounds. This chemical is a quinoline derivative, which is a class of compounds known for their diverse biological activities, including antimicrobial, anti-inflammatory, and antimalarial properties. The methyl ester form of 6-bromo-4-chloro-quinoline-2-carboxylic acid makes it more stable and easier to handle in laboratory settings, and it can be used as a building block for the synthesis of more complex molecules with potential pharmacological applications.
Check Digit Verification of cas no
The CAS Registry Mumber 887587-50-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,8,7,5,8 and 7 respectively; the second part has 2 digits, 5 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 887587-50:
(8*8)+(7*8)+(6*7)+(5*5)+(4*8)+(3*7)+(2*5)+(1*0)=250
250 % 10 = 0
So 887587-50-0 is a valid CAS Registry Number.
887587-50-0Relevant articles and documents
Synthesis of quinoline thioethers as novel small molecule enhancers of monoclonal antibody production in mammalian cell culture
Kazi, Shahid A.,Kelso, Geoffrey F.,Harris, Simon,Boysen, Reinhard I.,Chowdhury, Jamil,Hearn, Milton
scheme or table, p. 9461 - 9467 (2011/01/12)
A small library of novel quinoline derivatives containing different thioether substituents at position 4 have been synthesized and screened in murine hybridoma cell culture for their ability to enhance monoclonal antibody (mAb) production. From this set of compounds, four compounds have been discovered that enhanced immunoglobulin G (IgG) titer over negative control cultures due to an increase in specific productivity. These results demonstrate the utility of using organic synthesis and parallel ligand screening methods to discover novel cell culture additives that may be useful for increasing mAb yield in industrial biomanufacturing processes.
