887628-08-2Relevant academic research and scientific papers
Synthesis of thiol-modified peptide nucleic acids designed for post-assembly conjugation reactions
De Koning, Martijn C.,Petersen, Lene,Weterings, Jimmy J.,Overhand, Mark,Van Der Marel, Gijsbert A.,Filippov, Dmitri V.
, p. 3248 - 3258 (2007/10/03)
Two orthogonally protected PNA monomers were prepared having the mercaptomethyl moiety attached to the PNA backbone. These building blocks were employed in solid-phase PNA synthesis and it was shown that Boc/S-p- methoxybenzyl protection scheme was only s
