887646-95-9Relevant academic research and scientific papers
Synthesis and characterization of styrylchromone derivatives as β-amyloid imaging agents
Ono, Masahiro,Maya, Yoshifumi,Haratake, Mamoru,Nakayama, Morio
, p. 444 - 450 (2007)
Several promising agents have been synthesized and evaluated for in vivo imaging probes of β-amyloid plaques in Alzheimer's disease (AD) brain. Recently, we have developed flavone derivatives, which possess the basic structure of the 2-phenylchromone, as
COMPOUND FOR BORON NEUTRON CAPTURE THERAPY FOR AMYLOID β DISEASES
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Paragraph 0095, (2020/06/05)
PROBLEM TO BE SOLVED: To provide a boron carrier compound having high binding specificity to an amyloid β protein, high permeability through the blood brain barrier, and a retention property in senile plaques in the brain, while having a property less lik
COMPOSITION FOR AMYLOID-ASSOCIATED DISEASE DIAGNOSIS
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Page/Page column 5; 37-38; 44; 55, (2010/11/28)
A composition for diagnosing amyloid-related diseases, which comprises a flavone derivative, a chalcone derivative, a styrylchromone derivative, or a coumarin derivative, is provided. These compounds have high binding specificity to an amyloid β protein,
