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887707-21-3

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887707-21-3 Usage

General Description

(6-Chloro-5-methylpyridin-3-yl)methanol is a chemical compound that belongs to the class of pyridine derivatives. It is a white to off-white solid with a molecular formula of C7H7ClNO and a molecular weight of 157.59 g/mol. (6-CHLORO-5-METHYLPYRIDIN-3-YL)METHANOL is commonly used in the synthesis of pharmaceuticals, agrochemicals, and other organic compounds. It has potential applications in the field of medicine, particularly in the development of new drugs and treatments. Additionally, it can also be used as a building block in organic synthesis processes. Overall, (6-Chloro-5-methylpyridin-3-yl)methanol is a versatile and important chemical compound with a range of potential applications in various industries.

Check Digit Verification of cas no

The CAS Registry Mumber 887707-21-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,8,7,7,0 and 7 respectively; the second part has 2 digits, 2 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 887707-21:
(8*8)+(7*8)+(6*7)+(5*7)+(4*0)+(3*7)+(2*2)+(1*1)=223
223 % 10 = 3
So 887707-21-3 is a valid CAS Registry Number.

887707-21-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name (6-Chloro-5-methylpyridin-3-yl)methanol

1.2 Other means of identification

Product number -
Other names (6-chloro-5-methylpyridin-3-yl)methanol

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:887707-21-3 SDS

887707-21-3Relevant articles and documents

Design, synthesis, and evaluation of potent Wnt signaling inhibitors featuring a fused 3-ring system

Xu, Zhixiang,Li, Jiajun,Wu, Yiyuan,Sun, Zhijian,Luo, Lusong,Hu, Zhilin,He, Sudan,Zheng, Jiyue,Zhang, Hongjian,Zhang, Xiaohu

, p. 154 - 165 (2015/12/04)

The Wnt signaling pathway is a critical developmental pathway which operates through control of cellular functions such as proliferation and differentiation. Aberrant Wnt signaling has been linked to the formation and metastasis of tumors. Porcupine, a member of the membrane-bound O-acyltransferase family of proteins, is an important component of the Wnt pathway. Porcupine catalyzes the palmitoylation of Wnt proteins, a process needed for their secretion and activity. Here we report a novel series of compounds obtained by a scaffold hybridization strategy from a known porcupine inhibitor class. The leading compound 59 demonstrated subnanomolar inhibition of Wnt signaling in a paracrine cellular assay. Compound 59 also showed excellent chemical, plasma and liver microsomal stabilities. Furthermore, compound 59 exhibited good pharmacokinetic profiles with 30% oral bioavailability in rat. Collectively, these results strongly support further optimization of this novel scaffold to develop better Wnt pathway inhibitors.

COMPOUNDS

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Page/Page column 26, (2009/12/24)

Compounds of Formula (I) or pharmaceutically acceptable salts or N-oxides thereof: (relative chemistry shown) pharmaceutical compositions comprising them, their use in therapy especially against tuberculosis, and methods of preparing them are described.

Methyl, trifluoromethyl, and methoxycarbonyl - Introduction to the fifth position on the pyridine ring of chloronicotinyl insecticide imidacloprid

Kagabu, Shinzo

, p. 1235 - 1245 (2007/10/03)

Imidacloprid is the first chloronicotinyl insecticide and is currently the largest-selling insecticide worldwide. As a project to find its variants of different insecticidal spectra, derivatives substituted with methyl, trifluoromethyl, and methoxy-carbonyl at the fifth position on the pyridine ring of imidacloprid were prepared. Copyright Taylor & Francis Group, LLC.

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